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Evaluation of the new criteria of 2010 for diabetes mellitus: Japan Diabetes Society

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Abstract

We investigated the characteristics of the new criteria for diabetes mellitus (DM) issued by the Japan Diabetes Society in 2010, which include HbA1C measurement, and differences between 1999 criteria, in order to indicate clinical caution points. If a person with fasting plasma glucose (FPG) ≥126 mg/dl or an oral glucose tolerance test (OGTT) 2-h value ≥200 and HbA1C ≥6.5 % is determined as having DM, the disease can be detected at a rate of ≥70 % in persons <60 years and at no more than 40–50 % in elderly persons. In longitudinal examination, we observed that individuals with DM with FPG ≥126 mg/dl and HbA1C ≥6.5 % obtained the same determination over time at a rate of nearly 90 %. The percentage of persons whose result shifted from normal type to DM was 3- to 4-fold lower than that of persons whose result shifted from normal type to diabetic type. Based on these results, measurement of FPG and HbA1C at the same time may be extremely effective in identifying DM, although we should pay attention to a higher likelihood that mild glucose metabolism disorders will be overlooked.

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References

  1. Internal Expert Committee. Internal Expert Committee report on the role of the A1C assay in the diagnosis of diabetes. Diabetes Care. 2009;32:1327–34.

    Article  Google Scholar 

  2. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2010;33(Suppl 1):S62–9.

    Article  PubMed Central  Google Scholar 

  3. WHO. Use of glycated hemoglobin (HbA1C) in the diagnosis of diabetes mellitus. Geneva: Abbreviated Report of a WHO Consultation WHO; 2011.

  4. Kuzuya T, Nakagawa S, Satoh J, Kanazawa Y, Iwamoto Y, Kobayashi M, Nanjo K, Sakai A, Seino Y, Ito C, Shima K, Nonaka K, Kadowaki T. Report of the committee on the classification and diagnostic criteria of diabetes mellitus. J Jpn Diabetes Soc. (1999); 42:385–404. (in Japanese); This report appears in Englishi; Diabetes Res Clin Pract. (2002); 55:65-85.

  5. Report of the Committee on the classification and diagnostic criteria of diabetes mellitus, Seino Y, Nanjo K, Tajima N, Kadowaki T, Kashiwagi A, Araki E, Ito C, Inagaki N, Iwamoto Y, Kasuga M, Hanabusa T, Haneda K, Ueki K. Report of the Committee on the classification and diagnostic criteria of diabetes mellitus. Diabetol Int. 2010;1:2–20.

    Article  Google Scholar 

  6. Ito Chikako. Evidence for diabetes mellitus criteria in 2010 using HbA1C. Diabetol Int. 2013;4:9–15.

    Article  Google Scholar 

  7. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412–9.

    Article  CAS  PubMed  Google Scholar 

  8. Monnier L, Colette C, Dunseath GJ, Owens DR. The loss of postprandial glycemic control precedes stepwise deterioration of fasting with worsening diabetes. Diabetes Care. 2007;30:263–9.

    Article  PubMed  Google Scholar 

  9. Shima K. In: Shima K, editor. Glycohemoglobin seeing and thinking of plasma glucose. Tokyo: Nankodo; 2000. p. 51–61. (in Japanese).

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Correspondence to Rumi Fujikawa.

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All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later revision. Informed consent or substitute for it was obtained from all patients for being included in the study.

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The authors declare no conflict of interest.

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Fujikawa, R., Ito, C. & Kira, S. Evaluation of the new criteria of 2010 for diabetes mellitus: Japan Diabetes Society. Diabetol Int 7, 321–325 (2016). https://doi.org/10.1007/s13340-016-0253-3

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  • DOI: https://doi.org/10.1007/s13340-016-0253-3

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