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Childhood lupus with microangiopathic antiphospholipid syndrome and pulmonary hemorrhage

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Abstract

Background

Concurrent thrombotic and hemorrhagic manifestations are uncommon in patients with Antiphospholipid Syndrome.

Case characteristics

A 10-year-old girl with fever, edema, rash and joint pains, who later developed deep venous thrombosis (DVT), stroke, thrombotic microangiopathic hemolytic anemia and pulmonary hemorrhage. Investigations confirmed Antiphospholipid syndrome associated with systemic lupus erythematosus.

Outcome

She went into complete remission with intravenous immunoglobulins, plasmapheresis, immunosuppression and anticoagulation.

Message

Thrombotic microangiopathic hemolytic anemia and anti-phospholipid syndrome can be the presenting manifestations of systemic lupus erythematosus..

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Author information

Authors and Affiliations

  1. Departments of Nephrology, SGPGI, Lucknow, Uttar Pradesh, India

    Dharmendra Bhadauria, Praveen Etta & Anupma Kaul

  2. Departments of Renal Transplantation, SGPGI, Lucknow, Uttar Pradesh, India

    Narayan Prasad

Authors
  1. Dharmendra Bhadauria
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  2. Praveen Etta
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  3. Anupma Kaul
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  4. Narayan Prasad
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Corresponding author

Correspondence to Dharmendra Bhadauria.

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Bhadauria, D., Etta, P., Kaul, A. et al. Childhood lupus with microangiopathic antiphospholipid syndrome and pulmonary hemorrhage. Indian Pediatr 52, 333–338 (2015). https://doi.org/10.1007/s13312-015-0634-x

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  • DOI: https://doi.org/10.1007/s13312-015-0634-x

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