Abstract
Delayed gastric emptying (DGE) is a common complication after pancreaticoduodenectomy (PDD) significantly contributing to post-operative morbidity. Clinical risk factors for DGE occurrence after PDD remain controversial. From January 2004 to December 2011, a total of 132 patients underwent PDD for either malignancies (73.5 %) or benign diseases (26.5 %) in one single universitary center. Post-operative mortality and morbidity were, respectively, 3 and 44.7 %. DGE has been defined in accordance with the International Study Group of Pancreatic Surgery (ISGPS) classification. DGE was distinguished in primary or secondary. Factors associated with grades B and C of DGE, based on severity and clinical impact, were assessed by means of univariate and multivariate analysis. Thirty-eight patients (28.8 %) had clinical DGE grade B or C. Post-operative complications (pancreatic fistula and/or hemorrhage or anastomotic leak) were reported in 25 out of the 38 patients (65.8 %, secondary DGE), while in 13 patients it was not associated to any other complication (34.2 %, primary DGE). Post-operative complications (pancreatic fistula and hemorrhage) appeared to be the most important predictive factor for Grade B or C DGE.
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All procedures performed in the study involving human participants were in accordance with the ethical standards and /or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
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Data reported in this study does not contain experimentation on humans participants nor animals. Data were collected within standards medical procedures and after regular informed consent demanded to all patients enrolled.
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Courvoisier, T., Donatini, G., Faure, J.P. et al. Primary versus secondary delayed gastric emptying (DGE) grades B and C of the International Study Group of Pancreatic Surgery after pancreatoduodenectomy: a retrospective analysis on a group of 132 patients. Updates Surg 67, 305–309 (2015). https://doi.org/10.1007/s13304-015-0296-1
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DOI: https://doi.org/10.1007/s13304-015-0296-1