Abstract
Objectives
To study myometrial thickness (MT) sonographically as a predictor of latency interval in women with preterm premature rupture of membranes (PPROM).
Study design
The data were collected in a prospective manner from the antenatal patients between November 2011 and June 2013 during the follow-up of patients in the Department of Obstetrics and Gynecology, Goa Medical College. 100 patients with the periods of gestation of 28–36 weeks were studied, out of which 50 were PPROM cases and 50 were controls, both not in labor. The demographic factors and MT of uterine wall are measured at four different levels: midanterior, posterior, lower uterine segment (LUS), and fundus, which are then compared with the latency interval which is defined as the time from the rupture of membranes to the time of delivery.
Results
There was a significant inverse relation between the periods of gestation and latency interval, and positive correlation between anterior MT (p value 0.047), LUS thickness (p value 0.000), and latency interval implicating that the thicker the myometrium at admission in cases of PPROM the longer the latency period.
Conclusion
MT appears a promising tool for obstetricians for predicting latency in cases of PPROM and guiding the management.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Hamdi K, Bastani P, Saheb-Madarek EO, et al. Prediction of latency interval in preterm premature rupture of membranes using sonographic myometrial thickness. Pak J Biol Sci. 2010;13(17):841–6.
Buhimschi CS, Buhimschi IA, Norwitz ER, et al. Sonographic myometrial thickness predicts the latency interval of women with preterm premature rupture of the membranes and oligohydramnios. Am J Obstet Gynecol. 2005;193:762–70.
Kalantari M, et al. Correlation between myometrial thickness and the latency interval in preterm premature rupture of membranes. Iran J Radiol. 2010;7(4):215–9.
Singhal S, Puri M, Gami N. An analysis of factors affecting the duration of latency period and its impact on neonatal outcome in patients with PPROM. Arch Gynecol Obstet. 2011;284(6):1339–43.
Atarjavdan L, et al. Correlation of myometrial thickness and the latency interval of women with preterm premature rupture of the membranes. Arch Gynecol Obstet. 2011;284(6):1339–43.
Caughey AB, Robinson JN, Norwitz ER. Contemporary diagnosis and management of preterm premature rupture of the membranes. Winter. 2008;1(1):11–22.
Van der Ham DP, van der Heyden JL, Opmeer BC, et al. Management of late-preterm premature rupture of membranes: PPROMEXIL-2 trial. Am J Obstet Gynecol. 2012;207(276):e1–10.
Compliance with ethical requirements and Conflict of interest
The research is in compliance with ethical standards. Permissions have been taken and is approved by the institutional ethical committee. The authors declare that they have no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Additional information
Ajit Nagarsenkar is a Associate Professor in Goa Medical College, Bambolim, Goa, India.
Rights and permissions
About this article
Cite this article
Gupta, R., Nagarsenkar, A. Using Sonographically Estimated Myometrial Thickness in Prediction of Latency Interval in Cases of Preterm Premature Rupture of Membranes (PPROM). J Obstet Gynecol India 66, 431–435 (2016). https://doi.org/10.1007/s13224-015-0711-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13224-015-0711-z