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Prostatic Adenocarcinoma Incognito Manifestation as Generalized Lymphadenopathy: a Rare Case Report

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Abstract

Generalized lymphadenopathy is a rare manifestation of carcinoma prostate. Here, we report a case of a 73-year-old male who presented with left supraclavicular lymphadenopathy along with hoarseness of voice and weight loss. His CT neck, chest, abdomen, and subsequently18F-FDG PET CT were suggestive of generalized lymphadenopathy with skeletal involvement. He was not having any urinary or bone symptoms. The biopsy of supraclavicular lymph node revealed metastatic adenocarcinoma, whose prostatic origin was suggested by IHC staining of PSA. The diagnosis was confirmed by prostatic biopsy along with markedly raised serum PSA. We emphasize that in men with adenocarcinoma of undetermined origin, a suspicion of prostate cancer is important for accurate diagnosis and therapeutic approach.

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References

  1. Ferlay J., Shin H.R., Bray F. International Agency for research on Cancer, Lyon, France: 2010. GLOBOCAN 2008, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No.10.

  2. Mundy GR (2002) Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer 2(8):584–593

    Article  CAS  PubMed  Google Scholar 

  3. Jones H, Anthony PP (1992) Metastatic prostatic carcinoma presenting as left-sided cervical lymphadenopathy: a series of 11 cases. Histopathology 21(2):149–154

    Article  CAS  PubMed  Google Scholar 

  4. Sagalowsky AI, Wilson JD. Harrison’s principles of internal medicine. 14th edition. New York: McGraw-Hill; 1998. Hyperplasia and carcinoma of the prostate; pp. 596–602.

  5. Saitoh H, Hida M, Shimbo T, Nakamura K, Yamagata J, Satoh T (1984) Metastatic patterns of prostatic cancer. Correlation between sites and number of organs involved. Cancer 54(12):3078–3084

    Article  CAS  PubMed  Google Scholar 

  6. Flocks RH, Boatman DL (1973) Incidence of head and neck metastases from genito urinary neoplasms. Laryngoscope 83(9):1527–1539

    Article  CAS  PubMed  Google Scholar 

  7. Welsh LW, Chinnici JC, Welsh JJ, Huck. GF Jr (1982) Mediastinoscopy for extrathoracic malignancies. Ann Otol Rhinol Laryngol 91(6):659–665

  8. Batson OV (1995) The function of vertebral veins and their role in the spread of metastasis. ClinOrthopRelat Res 312:4–9

    Google Scholar 

  9. Furuya Y, Akakura K, Akimoto S, Ito H (1998) Prognosis of patients with prostate carcinoma presenting as nonregional lymph node metastases. Urol Int 61(1):17–21

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Amit Sehrawat.

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The authors declare that they have no conflict of interest.

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Key Messages

We emphasize that in men with adenocarcinoma of undetermined origin, a suspicion of prostate cancer is important for accurate diagnosis and therapeutic approach. Any elderly male presenting with generalized lymphadenopathy, prostate cancer metastasis should also be considered especially if the biopsy reveals adenocarcinoma of undetermined origin in a clinical setting of raised PSA

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Sehrawat, A., Gupta, S. & Alok, T. Prostatic Adenocarcinoma Incognito Manifestation as Generalized Lymphadenopathy: a Rare Case Report. Indian J Surg Oncol 8, 91–93 (2017). https://doi.org/10.1007/s13193-016-0558-5

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  • DOI: https://doi.org/10.1007/s13193-016-0558-5

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