Abstract
Primary angiosarcoma of the bone (PAB) is a rare and fatal high-grade malignant vascular bone tumor. We report a rare case of multicentric PAB mimicking bone metastasis in a 59-year-old female patient with a history of sigmoid colon cancer. This patient complained of lower back and pelvic pain and presented with multiple osteolytic bone lesions on plain radiography and pelvic computed tomography. First, bone metastasis of sigmoid colon cancer was suspected. However, on the 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) scan, the patient presented unusual multiple hypermetabolic osteolytic bone lesions involving contiguous bones of the lower half of the body. After bone biopsy, these lesions were confirmed to be multicentric PAB. To the best of our knowledge, this is the first case report of an 18F-FDG PET/CT scan in a patient with multicentric primary bone angiosarcoma.
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Conflict of Interest
Min Young Yoo, Eun Seong Lee, Seog-Yun Park, Seok-ki Kim, Youngmee Kwon, Tak Yun, and Tae Sung Kim declare that they have no conflict of interest.
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All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation and with the Helsinki Declaration of 1975, as revised in 2000. The study design and exemption of informed consent were approved by the Institutional Review Board of the National Cancer Center, Korea.
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Yoo, M.Y., Lee, E.S., Kim, Sk. et al. Multicentric Primary Angiosarcoma of Bone Mimicking Metastasis on 18F-FDG PET/CT in a Patient with a History of Sigmoid Colon Cancer: a Case Report. Nucl Med Mol Imaging 49, 321–324 (2015). https://doi.org/10.1007/s13139-015-0353-1
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DOI: https://doi.org/10.1007/s13139-015-0353-1