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Solitary Eosinophilic Granuloma of Mandibular Condyle: Literature Review and Report of a Rare Case

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Abstract

Solitary eosinophilic granuloma (EG) is traditionally included as 1 of the 3 clinical manifestations of the histiocytosis-X group of diseases, which also encompasses Hand–Schuller–Christian disease and Letterer–Siwe disease. EG is the most common lesion in the spectrum of disorders under the classification of Langerhans cell histiocytosis. EG represents the monostotic form of the disease with the head and neck region representing the most common site of initial presentation. We report a rare case of solitary EG involving mandibular condyle in a 49-year-old male patient, which is the first reported case in Indian literature.

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References

  1. Stewart JCB (1993) Benign non-odontogenic tumors. In: Regezi JA, Sciubba JJ (eds) Oral pathology: clinical pathologic correlations, 2nd edn. Saunders, Philadelphia, p 413

    Google Scholar 

  2. Stingl G, Kunihiko T, Katz SI (1980) Origin and function of epidermal Langerhans cells. Immunol Rev 53:149

    Article  CAS  PubMed  Google Scholar 

  3. Lombardi T, Hauser C, Budtz-Jorgensen E (1993) Langerhans’ cells: structure, function and role in oral pathological conditions. J Oral Pathol Med 22:193

    Article  CAS  PubMed  Google Scholar 

  4. Cline MJ (1994) Histiocytes and histiocytosis. Blood 84:2840

    CAS  PubMed  Google Scholar 

  5. Willman CL, Busque L, Griffith BB et al (1994) Langerhans’ cell histiocytosis (histiocytosis X): a clonal proliferative disease. N Engl J Med 331:154

    Article  CAS  PubMed  Google Scholar 

  6. Makek M, Sailer HF (1980) Eosinophilic granuloma of the mandibular condyle: case report. J Maxillofac Surg 8:327

    Article  CAS  PubMed  Google Scholar 

  7. Tant L, Dourov N, Vanatoru P et al (1984) Le granulome eosinophile (histiocytose X): a propos d’un cas de localisation au niveau du condyle mandibulaire. Acta Stomatol Belg 81:181

    CAS  PubMed  Google Scholar 

  8. Zachariades N, Anastasea-Vlachou K, Xypolyta A et al (1987) Uncommon manifestations of histiocytosis X. Int J Oral Maxillofac Surg 16:355

    Article  CAS  PubMed  Google Scholar 

  9. Peckitt NS, Wood GA (1988) Eosinophilic granuloma of the mandibular condyle. Br J Oral Maxillofac Surg 26:306

    Article  CAS  PubMed  Google Scholar 

  10. Dagenais M, Pharoah MJ, Sikorski PA (1992) The radiographic characteristics of histiocytosis X: a study of 29 cases that involve the jaws. Oral Surg Oral Med Oral Pathol 74:230

    Article  CAS  PubMed  Google Scholar 

  11. Bhaskar PB, White CS, Baughman RA (1993) Eosinophilic granuloma of the mandibular condyle: a case report and management discussion. Oral Surg Oral Med Oral Pathol 76:557

    Article  CAS  PubMed  Google Scholar 

  12. Wong GB, Pharoah hlJ, Weinberg S et al (1997) Eosinophilic granuloma of the mandibular condyle: report of three cases and review of the literature. J Oral Maxillofac Surg 55:870

    Article  CAS  PubMed  Google Scholar 

  13. Donazzan M, Pellerin P, Seck JP, Leclercq A (1981) Mandibular condyle lacunae (a report on three cases (aneurysmal cyst, granuloma eosinophil and metastasis)). Rev Stomatol Chir Maxillofac 82:113–120

    CAS  PubMed  Google Scholar 

  14. Roychoudhury A, Shah N, Parkash H et al (1998) Eosinophilic granuloma of the jaws. Br J Oral Maxillofac Surg 36:380

    Article  CAS  PubMed  Google Scholar 

  15. Henry RJ, Sweeney EA (1996) Langerhans’ cell histiocytosis: case reports and literature review. Pediatr Dent 81:11

    Google Scholar 

  16. Hartman KS (1980) Histiocytosis X: a review of 114 cases with oral involvement. Oral Surg Oral Med Oral Pathol 49:38

    Article  CAS  PubMed  Google Scholar 

  17. Whitcher BL, Webb DJ (1986) Treatment of recurrent eosinophilic granuloma of the mandible following radiation therapy. J Oral Maxillofac Surg 44:565

    Article  CAS  PubMed  Google Scholar 

  18. Wester SM, Beabout JW, Unni KK et al (1982) Langerhans cell granulomatosis (histiocytosis X) of bone in adults. Am J Surg Pathol 6:413

    Article  CAS  PubMed  Google Scholar 

  19. Slater JM, Swarm OJ (1980) Eosinophilic granuloma of bone. Med Pediatr Oncol 8:151

    Article  CAS  PubMed  Google Scholar 

  20. Gorsky M, Silverman S, Lozada F et al (1983) Histiocytosis X: occurrence and oral involvement in six adolescent and adult patients. Oral Surg Oral Med Oral Pathol 55:24

    Article  CAS  PubMed  Google Scholar 

  21. Cleveland DB, Goldberg KM, Greenspan JS et al (1996) Langerhans cell histiocytosis: report of three cases with unusual oral soft tissue involvement. Oral Surg Oral Med Oral Pathol 82:541

    Article  CAS  Google Scholar 

  22. Kumar R (1980) Relative roles of radionuclide scanning and radiographic imaging in eosinophilic granuloma. Clin Nucl Med 5:538

    Article  CAS  PubMed  Google Scholar 

  23. Ardekian L, Peled M, Rosen D et al (1999) Clinical and radiographic features of eosinophilic granuloma in the jaws. Review of 41 lesions treated by surgery and low-dose radiotherapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 87:238

    Article  CAS  PubMed  Google Scholar 

  24. Gnanasekhar JD, Ahmad MS, Reddy RR (1991) Multifocal Langerhans cell histiocytosis of the jaws: a case report. Quintessence Int 22:559

    CAS  PubMed  Google Scholar 

  25. Jones LR, Toth BB, Cangir A (1989) Treatment for eosinophilic granuloma of the mandible by steroid injection. J Oral Maxillofac Surg 47:306

    Article  CAS  PubMed  Google Scholar 

  26. Biswal BM, Sandhu M, Lal P et al (1995) Solitary eosinophilic granuloma of the mandible. J Indian Med Assoc 93:463

    CAS  PubMed  Google Scholar 

  27. Miyamoto H, Dance G, Wilson DF, Goss AN (2000) Eosinophilic granuloma of the mandibular condyle. J Oral Maxillofac Surg 58:560–562

    Article  CAS  PubMed  Google Scholar 

  28. Hood David C, Miller Frank R, Drawert Casey (2004) Solitary eosinophilic granuloma in the ramus and condyle of the mandible report. Otolaryngol Head Neck Surg 131:306

    Article  Google Scholar 

  29. Tauro DP, Agarwal Sumit, Kamath RAD, Shashikala P (2011) Resolution of eosinophilic granuloma of the mandibular ramus and condylar neck following minimal intervention—report of a case and review of literature. Asian J Oral Maxillofac Surg 23:138–142

    Article  Google Scholar 

  30. Kazunari Nishihara, Kojiro Onizawa, Tomono Namai et al (2003) A case of eosinophilic granuloma of the mandibular condyle. Jpn J Oral Maxillofac Surg 49:666–669

    Article  Google Scholar 

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Correspondence to Yadavalli Guruprasad.

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Guruprasad, Y., Chauhan, D.S. Solitary Eosinophilic Granuloma of Mandibular Condyle: Literature Review and Report of a Rare Case. J. Maxillofac. Oral Surg. 14 (Suppl 1), 209–214 (2015). https://doi.org/10.1007/s12663-012-0438-7

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  • DOI: https://doi.org/10.1007/s12663-012-0438-7

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