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Association of Daily Physical Activity with Disability in Community-Dwelling Older Adults With/Without Chronic Kidney Disease

  • Original Research
  • Published:
The journal of nutrition, health & aging

Abstract

Objectives

Physical activity is recommended for disability prevention in the older adult population; however, the level of physical activity required for older adults with chronic kidney disease (CKD) remains unknown. This study aimed to examine the associations between daily physical activity and disability incidence in older adults with and without CKD to determine relevant daily physical activity levels.

Design

Prospective observational study.

Setting and Participants

3,786 community-dwelling older adults aged ≥65 years.

Measurements

Mean daily times spent in light- (LPA) and moderate-to-vigorous physical activity (MVPA) were measured using triaxial accelerometers. CKD was defined by a creatinine estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m2. Disability incidence was identified as long-term care insurance certification during a 60-month follow-up period. Associations between physical activity and disability incidence were examined using Cox proportional hazard models stratified by the CKD status. Non-linear and linear associations were tested using the restricted cubic spline.

Results

A total of 1,054 individuals were identified to have CKD. Disability incidence was higher in the CKD group than in the non-CKD group. The adjusted cox proportional hazard models indicated that a 10-minute increase in MVPA time was associated with lower disability incidence in the non-CKD group (hazard ratio [HR], 0.838; 95% confidence interval [CI]: 0.764–0.918) and the CKD group (HR, 0.859; 95% CI: 0.766–0.960). Linear associations were observed in MVPA for the non-CKD and CKD groups.

Conclusion

Increasing MVPA was associated with lower disability incidence in older adults with and without CKD. These findings can help devise disability prevention strategies for older CKD patients.

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Acknowledgement

We thank the healthcare staff for their valued assistance with the study assessments. We would like to thank Editage (https://www.editage.jp) for English language editing. We would like to thank the JSPS KAKENHI Grant-in-Aid for Young Scientists (grant number: 20K18975) for their support.

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Authors and Affiliations

  1. Department of Preventive Gerontology, Centre for Gerontology and Social Science, National Centre for Geriatrics and Gerontology, 7-430, Morioka-cho, Obu, City, Aichi, 474-8511, Japan

    Ippei Chiba, S. Lee, S. Bae, K. Makino, O. Katayama, K. Harada, K. Tomida, M. Morikawa & H. Shimada

  2. Department of Medical Sciences, Medical Science division, Graduate School of Medicine, Science and Technology, Shinshu University, Matsumoto, Japan

    Ippei Chiba & H. Shimada

  3. Tokyo Research Laboratories, Kao Corporation, Sumida-ku, Tokyo, Japan

    Y. Yamashiro & N. Takayanagi

  4. Japan Society for the Promotion of Science, Chiyoda-ku, Tokyo, Japan

    K. Makino & O. Katayama

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  1. Ippei Chiba
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  2. S. Lee
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Contributions

Author contributions: IC was involved in study concept and design, data interpretation, and the manuscript preparation. SL, SB, KM and KH involved in the acquisition of subjects and data. OK, KT, MM, YY and NT critically revised the report, commented on the drafts of manuscript. HS approved the final report.

Corresponding author

Correspondence to Ippei Chiba.

Ethics declarations

Ethical Standards: Ethical standards for epidemiological study were adhered to according to guidelines from the Ministry of Health, Labour and Welfare, Japan.

Conflicts of interest: The work in Takahama city was supported by a Research Funding for Longevity Sciences (27–22) from the NCGG, Grant-in-Aid for Scientific Research (A) (26242059), joint research with Kao Corporation, and expenses for R&D were commissioned by Takahama city. This work in Nagoya city was supported by the Strategic Basic Research Programs Redesigning Communities for Aged Society (RISTEX) of the Japan Science and Technology Agency (JST), Health and Labor Sciences Research Grants, and joint research with Kao Corporation.

Additional information

Sponsors role: Kao corporation provided the accelerometers. Other funders played no role in the design, methods, subject recruitment, data collections, analysis and preparation or paper.

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Chiba, I., Lee, S., Bae, S. et al. Association of Daily Physical Activity with Disability in Community-Dwelling Older Adults With/Without Chronic Kidney Disease. J Nutr Health Aging 26, 521–528 (2022). https://doi.org/10.1007/s12603-022-1790-z

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  • DOI: https://doi.org/10.1007/s12603-022-1790-z

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