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Prognosis of stress-only SPECT myocardial perfusion imaging with prone imaging

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Journal of Nuclear Cardiology Aims and scope

Abstract

Background

Stress-only single-photon emission computed tomography myocardial perfusion imaging (SO SPECT MPI) is associated with similarly benign prognosis as stress-rest SPECT MPI. However, previous studies have used attenuation correction rather than prone imaging to increase the rate of SO studies.

Objectives

To assess the prognosis of SO SPECT MPI performed with prone imaging.

Methods

We performed a retrospective cohort analysis of all patients who underwent a Tc-99m gated SPECT MPI over a 58-month period.

Results

Two thousand four hundred and sixty five patients were followed up. Of them, 1114 (45.2%) patients had a SO supine test, 388 (15.7%) underwent a SO supine and prone test, and the remaining 963 (39.1%) patients underwent a full stress-rest SPECT MPI. There was a similar annual mortality rate between the SO supine/prone group (1.3%), the SO supine (1.5%), and the stress-rest (1.5%) group (P = 0.47). Patients in the stress-rest group were significantly more likely to suffer from myocardial infarction (MI) as compared to the other two groups with an annual rate of 0.7% as compared to 0.4% (P = 0.049).

Conclusions

Normal supine-prone SO SPECT MPI is associated with a similarly benign prognosis as stress-rest SPECT MPI. The adjunction of prone imaging to the stress supine significantly increases the rate of SO SPECT MPI

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Abbreviations

SO:

Stress-only

SPECT:

Single-photon emission computed tomography

MPI:

Myocardial perfusion imaging

CAD:

Coronary artery disease

AC:

Attenuation correction

CABG:

Coronary artery bypass graft

PCI:

Percutaneous coronary intervention

MI:

Myocardial infarction

LV:

Left ventricular

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Disclosures

None of the authors has any conflict of interest regarding this study.

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Correspondence to Ariel Gutstein MD or Nili Zafrir MD.

Additional information

See related editorial, doi:10.1007/s12350-016-0691-0.

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Gutstein, A., Bental, T., Solodky, A. et al. Prognosis of stress-only SPECT myocardial perfusion imaging with prone imaging. J. Nucl. Cardiol. 25, 809–816 (2018). https://doi.org/10.1007/s12350-016-0617-x

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  • DOI: https://doi.org/10.1007/s12350-016-0617-x

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