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Gastric intramucosal adenocarcinoma with an invasive micropapillary carcinoma component

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Abstract

A 70-year-old woman was referred to our hospital because of early gastric cancer (lesser curvature of the antrum, 0-IIc, tub1, 15 mm) and underwent endoscopic submucosal dissection. Microscopically, the lesion was found to be confined to the mucosa, and predominantly composed of well-differentiated tubular adenocarcinoma with a micropapillary component. On immunohistochemical examination, the characteristic “inside-out pattern” of the micropapillary component was observed; thus, we diagnosed the lesion as gastric cancer with a micropapillary component. Invasive micropapillary carcinoma is a rare subtype of gastric carcinoma, and, to our knowledge, this is the first case of invasive micropapillary carcinoma of the stomach confined to the mucosa.

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Disclosures

Conflict of interest

H. Tanaka, Y. Baba, T. Sase, Y. Isono, S. Matsusaki, T. Saito, H. Okano, K. Mukai, T. Murata, G. Watanabe declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Gastroenterology, Suzuka General Hospital, Yamanohana, Yasuzuka, Suzuka-Shi, Mie, 1275-53, Japan

    Hiroki Tanaka, Tomohiro Sase, Yoshiaki Isono, Shimpei Matsusaki, Tomonori Saito, Hiroshi Okano & Katsumi Mukai

  2. Department of Pathology, Suzuka General Hospital, Yamanohana, Yasuzuka, Suzuka-Shi, Mie, 1275-53, Japan

    Youichirou Baba & Tetsuya Murata

  3. Division of Molecular and Diagnostic Pathology, Niigata University, 754, Ichibancho, Asahimachidori, Chuo-ku, Niigata-Shi, Niigata, Japan

    Gen Watanabe

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  1. Hiroki Tanaka
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  2. Youichirou Baba
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  3. Tomohiro Sase
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  4. Yoshiaki Isono
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  5. Shimpei Matsusaki
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  6. Tomonori Saito
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  7. Hiroshi Okano
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  8. Katsumi Mukai
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  9. Tetsuya Murata
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  10. Gen Watanabe
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Correspondence to Hiroki Tanaka.

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Tanaka, H., Baba, Y., Sase, T. et al. Gastric intramucosal adenocarcinoma with an invasive micropapillary carcinoma component. Clin J Gastroenterol 8, 14–17 (2015). https://doi.org/10.1007/s12328-014-0541-z

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  • DOI: https://doi.org/10.1007/s12328-014-0541-z

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