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Unilateral Gynaecomastia in a Young Man with Chronic Myeloid Leukemia

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Abstract

Male reproductive issues are frequently overlooked in patients of chronic myeloid leukemia (CML) on imatinib therapy. Current article describes a young man with CML on imatinib mesylate since 13 years who presented to us with painful left sided breast swelling. Mammography and fine needle aspiration cytology confirmed the diagnosis of gynaecomastia and hormone profile revealed low testosterone levels. Gynaecomastia was attributed to imatinib related hypogonadism. Gynaecomastia improved after hormone replacement therapy. Need for long term monitoring of reproductive hormones in patients of CML on imatinib therapy is emphasized in this report.

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Authors and Affiliations

  1. Department of Medicine, 4th floor Nehru Hospital, PGIMER, Chandigarh, 160012, India

    Ankur Jain, Subhash Varma & Pankaj Malhotra

  2. Department of Cytology and Gynecological Pathology, PGIMER, Chandigarh, India

    Rashi Garg

Authors
  1. Ankur Jain
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  2. Subhash Varma
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  3. Rashi Garg
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  4. Pankaj Malhotra
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Corresponding author

Correspondence to Pankaj Malhotra.

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Nil.

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Obtained from the patient prior to publication of any material.

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The article follows the ethical guidelines as laid under Helsinki’s declaration 1976.

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Jain, A., Varma, S., Garg, R. et al. Unilateral Gynaecomastia in a Young Man with Chronic Myeloid Leukemia. Indian J Hematol Blood Transfus 33, 448–450 (2017). https://doi.org/10.1007/s12288-016-0762-z

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  • DOI: https://doi.org/10.1007/s12288-016-0762-z

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