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Spontaneous Regression of a Clinically-Advanced Histologically Low-Grade Follicular Lymphoma Involving the Breast: Case Report and Review of the Literature

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Indian Journal of Hematology and Blood Transfusion Aims and scope Submit manuscript

Abstract

A 68-year-old woman was diagnosed as having grade 1 follicular lymphoma of the left breast in November 2012. Bone marrow infiltration was noted histologically and confirmed by Southern blot analysis of the IgHJH locus. The clinical stage was IVA, advanced stage. According to the Follicular Lymphoma International Prognostic Index, the patient was classified into the high risk group. The general condition was good and there were no organ symptoms, therefore, the patient was kept under observation without treatment. After one year and 2 months of follow up, The mass was regressed spontaneously. As previous studies have suggested a poor prognosis of patients with an advanced clinical stage of the disease, careful follow-up of our patient is necessary.

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Authors and Affiliations

  1. Department of Hematology, Juntendo University Urayasu Hospital, 1-1, 2-chome, Tomioka, Urayasu, Chiba Prefecture, 279-0021, Japan

    Yasunobu Sekiguchi, Asami Shimada, Mutsumi Wakabayashi, Keiji Sugimoto & Masaaki Noguchi

  2. Shibanishi Clinic, Shimada-Setsubi Building 1F, 27-16, 2-chome, Shibanishi, Kawaguchi, Saitama Prefecture, 333-0855, Japan

    Hidenori Imai

  3. Department of Laboratory Medicine, Juntendo University, Urayasu Hospital, 1-1 2-chome, Tomioka, Urayasu, Chiba Prefecture, 279-0021, Japan

    Noriko Nakamura & Tomohiro Sawada

  4. Department of Hematology, Juntendo University Hospital, 3-1-3 Hongo, Bunkyo-ku, Tokyo, 113-8431, Japan

    Asami Shimada & Norio Komatsu

Authors
  1. Yasunobu Sekiguchi
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  2. Asami Shimada
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  4. Mutsumi Wakabayashi
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  5. Keiji Sugimoto
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  6. Noriko Nakamura
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  7. Tomohiro Sawada
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  9. Masaaki Noguchi
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Correspondence to Yasunobu Sekiguchi.

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Sekiguchi, Y., Shimada, A., Imai, H. et al. Spontaneous Regression of a Clinically-Advanced Histologically Low-Grade Follicular Lymphoma Involving the Breast: Case Report and Review of the Literature. Indian J Hematol Blood Transfus 30 (Suppl 1), 320–324 (2014). https://doi.org/10.1007/s12288-014-0382-4

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  • DOI: https://doi.org/10.1007/s12288-014-0382-4

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