Skip to main content

Advertisement

SpringerLink
Log in

Pancytopenia and Isolated Bone Marrow Recurrence in a Case of Previously Resected Gastric Carcinoma: A Rare Finding

  • Case Report
  • Published:
Indian Journal of Hematology and Blood Transfusion Aims and scope Submit manuscript

Abstract

Recurrences in resected cases of gastric carcinomas are well known. However isolated involvement of bone marrow is a rare presentation. We present a previously treated case of gastric carcinoma-signet-ring cell type who had a progressive shortness of breath since 1 month. A hemogram done at this occasion showed pancytopenia and leucoerythroblastic picture. Bone marrow examination revealed infiltration by signet-ring cells. All such patients who presents with unexplained pancytopenia should prompt us to suspect a bone marrow recurrence.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  1. Maehara Y, Sakaguchi Y, Moriguchi S, Orita H, Korenaga D, Kohnoe S et al (1992) Signet ring cell carcinoma of stomach. Cancer 69:1645–1650

    Article  PubMed  CAS  Google Scholar 

  2. Katai H, Maruyama K, Sasako M, Sano T, Okajima K, Kinoshita T et al (1994) Mode of recurrence after gastric cancer surgery. Dig Surg 11:99–103

    Article  Google Scholar 

  3. Noda N, Sano T, Shirao K, Ono H, Katai H, Sasako M et al (1996) A case of bone marrow recurrence from gastric carcinoma after a nine-year disease-free interval. Jpn J Clin Oncol 26:472–475

    Article  PubMed  CAS  Google Scholar 

  4. Ahn JB, Ha TK, Kwon SJ (2011) Bone metastasis in gastric cancer patients. J Gastric Cancer 11:38–45

    Article  PubMed  PubMed Central  Google Scholar 

  5. Blanchette P, Lipton JH, Barth D, Mackay H (2013) Case report of very late gastric cancer recurrence. Curr Oncol 20(2):161–164

    Article  Google Scholar 

  6. Sano T, Sasako M, Kinoshita T, Maruyama K (1993) Recurrence of early gastric cancer. Follow-up of 1475 patients and review of the Japanese literature. Cancer 72:3174–3178

    Article  PubMed  CAS  Google Scholar 

  7. Yoshikawa K, Kitaoka H (1983) Bone metastasis of gastric cancer. Jpn J Surg 13:173–176

    Article  PubMed  CAS  Google Scholar 

  8. Park HS, Rha SY, Kim HS, Hyung WJ, Park JS, Chung HC et al (2011) A prognostic model to predict clinical outcome in gastric cancer patients with bone metastasis. Oncology 80:142–150

    Article  PubMed  Google Scholar 

  9. Kim HS, Yi SY, Jun HJ, Lee J, Park JO, Park YS et al (2007) Clinical outcomes of gastric cancer patients with bone marrow metastasis. Oncology 73:192–197

    Article  PubMed  Google Scholar 

  10. Kusumoto H, Haraguchi M, Nozuka Y, Oda Y, Tsuneyoshi M, Iguchi H (2006) Characteristic features of disseminated carcinomatosis of bone marrow due to gastric cancer: the pathogenesis of bone destruction. Oncol Rep 16:735–740

    PubMed  Google Scholar 

  11. Etoh T, Baba H, Taketomi A, Nakashima H, Kohnoe S, Seo Y et al (2006) Diffuse bone metastasis and hematologic disorders from gastric cancer: clinicopathological features and prognosis. Oncol Rep 16:735–740

    Google Scholar 

  12. Rhee J, Han SW, Oh DY, Im SA, Kim TY, Bang YJ (2010) Clinicopathologic features and clinical outcomes of gastric cancer that initially presents with disseminated intravascular coagulation: a retrospective study. J Gastroenterol Hepatol 25:1537–1542

    Article  PubMed  Google Scholar 

  13. Morimatsu M, Shirouzu K, Irie K, Tokunaga O, Sasaguri Y (1985) Gross and microscopic characteristics of stomach cancer with microangiopathic hemolytic anemia and/or disseminated intravascular coagulopathy. Acta Pathol Jpn 35:809–822

    PubMed  CAS  Google Scholar 

Download references

Conflict of interest

The authors have no conflicts of interest to declare.

Author information

Authors and Affiliations

  1. Department of Haematology, Postgraduate Institute of Medical Education & Research, Level 5, Research Block A, Sector 12, Chandigarh, 160012, India

    Tushar Sehgal, Narender Kumar & Pulkit Rastogi

  2. Department of Radiotherapy, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India

    Rakesh Kapoor

Authors
  1. Tushar Sehgal
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Narender Kumar
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Pulkit Rastogi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Rakesh Kapoor
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Narender Kumar.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sehgal, T., Kumar, N., Rastogi, P. et al. Pancytopenia and Isolated Bone Marrow Recurrence in a Case of Previously Resected Gastric Carcinoma: A Rare Finding. Indian J Hematol Blood Transfus 30 (Suppl 1), 314–316 (2014). https://doi.org/10.1007/s12288-014-0378-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12288-014-0378-0

Keywords

Search

Navigation