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Chromosomal mosaicism for inversion of chromosome 3(p25, p26) in a case of idiopathic hypereosinophilic syndrome (IHES)

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Abstract

Cytogenetic analysis and molecular genetic studies help for diagnosis of IHES and differentiation between IHES and other hematologic disorders with eosinophilia. We want to present a case of IHES with chromosomal mosaicism for inversion of chromosome 3(p25, p26), who achieved complete remission after treatment with Imatinib and short course of prednisolone.

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Acknowledgments

Our special thank to M. Yaghmaie, Ph. D in Medical Genetics and all other laboratory stuff of Cytogenetic Lab. of Hematology, Oncology and BMT research center in Shariati Hospital in Tehran, Iran especially that performed Karyotype analysis for this patient.

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The authors declare that there are no conflicts of interests.

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  1. Devision of Hematology/Medical Oncology, Urmia University of Medical Sciences, Emam Khomeini Hospital, Urmia, Iran

    Nasim Valizadeh

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  1. Nasim Valizadeh
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Correspondence to Nasim Valizadeh.

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Valizadeh, N. Chromosomal mosaicism for inversion of chromosome 3(p25, p26) in a case of idiopathic hypereosinophilic syndrome (IHES). Indian J Hematol Blood Transfus 29, 55–57 (2013). https://doi.org/10.1007/s12288-011-0131-x

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  • DOI: https://doi.org/10.1007/s12288-011-0131-x

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