Abstract
The analysis of mutants is one of the most powerful ways to determine gene functions. However, for mutants that are generated by random mutagenesis, it often takes years of laboratory work to discover the causative mutations. Recently the advent of next-generation sequencing techniques has made whole-genome sequencing a viable alternative to detect mutations. This approach can be used for basic research, but also for the identification of mutations in human genes causing heritable diseases.
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Minou Nowrousian 1991–1996 Biologiestudium an der Ruhr-Universität Bochum. 1998 Promotion bei Prof. Dr. U. Kück am Lehrstuhl für Allgemeine und Molekulare Botanik in Bochum. 1999–2001 Postdoc bei Prof. Dr. J. Dunlap und Prof. Dr. J. Loros, Dartmouth Medical School, Hanover, NH, USA. 2007 Habilitation. Seit 2002 Projektleiterin am Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr-Universität Bochum.
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Nowrousian, M. Genomsequenzierung zur Identifikation von Mutationen. Biospektrum 19, 25–27 (2013). https://doi.org/10.1007/s12268-013-0265-5
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DOI: https://doi.org/10.1007/s12268-013-0265-5