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Rushhour — Phospholipidtransport an mitochondrialen Membranen

Schwerpunkt Mitochondrien

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Abstract

The functionality of mitochondrial membranes depends on the balanced accumulation of proteins and phospholipids. The endoplasmic reticulum serves both as donor membrane of precursor lipids and acceptor membrane for phospholipids synthesized within mitochondria, pointing to intense intermembrane lipid transport. The identification of mitochondrial lipid transfer proteins and of protein complexes tethering mitochondrial and ER membranes now provides insights into the molecular mechanisms of these phospholipid trafficking events.

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Authors and Affiliations

  1. Institut für Genetik, Universität zu Köln, Köln, Germany

    Christoph Potting & Thomas Langer

  2. Institut für Genetik, Universität zu Köln, Zülpicher Straß 47a, D-50674, Köln, Germany

    Thomas Langer

Authors
  1. Christoph Potting
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  2. Thomas Langer
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Correspondence to Thomas Langer.

Additional information

Christoph Potting 2002–2007 Biologiestudium an der Universität Köln. 2008–2011 Promotion (Dr. rer. nat.) am Institut für Genetik der Universität Köln und dem Max-Planck- Institut für Biologie des Alterns. Seit 2012 Postdoc am Institut für Genetik der Universität Köln.

Thomas Langer 1984–1989 Biologiestudium an der Universität Regensburg. 1989–1993 Promotion (Dr. rer. nat.) an der LMU München und am Memorial Sloan Kettering Cancer Center, New York, USA. 1994–2001 Postdoc und Arbeitsgruppenleiter am Institut für Physiologische Chemie der LMU München. Seit 2001 Professor am Institut für Genetik der Universität Köln.

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Potting, C., Langer, T. Rushhour — Phospholipidtransport an mitochondrialen Membranen. Biospektrum 19, 19–21 (2013). https://doi.org/10.1007/s12268-013-0263-7

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  • DOI: https://doi.org/10.1007/s12268-013-0263-7

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