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Multienzymnetzwerke für die Feinchemie

  • Wissenschaft
  • Komplexe in vitro-Systeme
  • Published:
BIOspektrum Aims and scope

Zusammenfassung

Die Produktion von Feinchemikalien beruht auf Prozessen mit mehreren Reaktionsschritten. Wir arbeiten an Konzepten für die Rekrutierung, Isolierung und Optimierung von in vitro-Enzymkaskaden aus Zellextrakten für die Synthese von komplexen Zuckern.

Abstract

The production of fine chemicals relies on complex multi-step synthesis. We work on the scientific and technical challenges to recruit, insulate and optimize multi-enzyme in vitro networks from cell free extracts for the synthesis of complex sugars.

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Author information

Authors and Affiliations

  1. Department für Biosysteme, ETH Zürich, Basel, Schweiz

    Matthias Bujara, Sonja Billerbeck & Sven Panke

  2. Department of Biosystems Science and Engineering, ETH Zürich, Mattenstraße 26, CH-4058, Basel, Schweiz

    Sven Panke

Authors
  1. Matthias Bujara
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  2. Sonja Billerbeck
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  3. Sven Panke
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Corresponding author

Correspondence to Sven Panke.

Additional information

Matthias Bujara Jahrgang 1980. 2001–2007 Biotechnologiestudium an der TU Braunschweig; Diplomarbeit in Infektionsbiologie. 2005–2006 Austausch und Studienarbeit an der University of Waterloo, Kanada. 2007 Onkologische Forschung, Nycomed GmbH, Konstanz. Seit 2007 Doktorand am Bioprozesslabor ETH Zürich, Schweiz.

Sonja Billerbeck Jahrgang 1982. 2001–2007 Biologiestudium an der Universität Tübingen. Diplomarbeit am Max-Planck-Institut für Entwicklungsbiologie, Tübingen. 2004–2005 Studium an der Universidade de São Paulo, Riberão Preto, Brasilien. Seit 2008 Doktorandin am Bioprozesslabor ETH Zürich, Schweiz.

Sven Panke Jahrgang 1967. 1989–1995 Biotechnologiestudium in Braunschweig und Madrid, Spanien. 1995–1999 Promotion an der ETH Zürich, Schweiz. 1999–2001 Wissenschaftler bei DSM Research, Geleen, Niederlande. Seit 2001 Assistenz- und außerordentlicher Professor für Bioverfahrenstechnik an der ETH Zürich.

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Bujara, M., Billerbeck, S. & Panke, S. Multienzymnetzwerke für die Feinchemie. Biospektrum 17, 399–401 (2011). https://doi.org/10.1007/s12268-011-0061-z

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  • DOI: https://doi.org/10.1007/s12268-011-0061-z

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