References
Tozzi MG, Camici M, Pesi R, Allegrini S, Sgarrella F, Ipata PL (1991) Nucleoside phosphotransferase activity of human colon carcinoma cytosolic 5′-nucleotidase. Arch Biochem Biophys 291:212–217
Meyer JA, Wang J, Hogan LE, Yang JJ, Dandekar S, Patel JP, Tang Z, Zumbo P, Li S, Zavadil J, Levine RL, Cardozo T, Hunger SP, Raetz EA, Evans WE, Morrison DJ, Mason CE, Carroll WL (2013) Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia. Nat Genet 45:290–294
Tzoneva G, Perez-Garcia A, Carpenter Z, Khiabanian H, Tosello V, Allegretta M, Paietta E, Racevskis J, Rowe JM, Tallman MS, Paganin M, Basso G, Hof J, Kirschner-Schwabe R, Palomero T, Rabadan R, Ferrando A (2013) Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL. Nat Med 19:368–371
Oh JE, An CH, Yoo NJ, Lee SH (2011) Detection of low-level EGFR T790M mutation in lung cancer tissues. APMIS 119:403–411
Yoo NJ, Kim HR, Kim YR, An CH, Lee SH (2012) Somatic mutations of the KEAP1 gene in common solid cancers. Histopathology 60:943–952
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This work was supported by a grant from National Research Foundation of Korea (2012R1A5A2047939).
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Hye Rim Oh and Youn Jin Choi contributed equally to this work.
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Oh, H.R., Choi, Y.J., Yoo, N.J. et al. Leukemia Relapse-Associated Mutation of NT5C2 Gene is Rare in de Novo Acute Leukemias and Solid Tumors. Pathol. Oncol. Res. 22, 223–224 (2016). https://doi.org/10.1007/s12253-015-9965-0
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DOI: https://doi.org/10.1007/s12253-015-9965-0