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Usefulness of model-based iterative reconstruction in semi-automatic volumetry for ground-glass nodules at ultra-low-dose CT: a phantom study

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Abstract

This study aimed to investigate the effects of parameter presets of the forward projected model-based iterative reconstruction solution (FIRST) on the accuracy of pulmonary nodule volume measurement. A torso phantom with simulated nodules [diameter: 5, 8, 10, and 12 mm; computed tomography (CT) density: − 630 HU] was scanned with a multi-detector CT at tube currents of 10 mA (ultra-low-dose: UL-dose) and 270 mA (standard-dose: Std-dose). Images were reconstructed with filtered back projection [FBP; standard (Std-FBP), ultra-low-dose (UL-FBP)], FIRST Lung (UL-Lung), and FIRST Body (UL-Body), and analyzed with a semi-automatic software. The error in the volume measurement was determined. The errors with UL-Lung and UL-Body were smaller than that with UL-FBP. The smallest error was 5.8% ± 0.3 for the 12-mm nodule with UL-Body (middle lung). Our results indicated that FIRST Body would be superior to FIRST Lung in terms of accuracy of nodule measurement with UL-dose CT.

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Acknowledgements

The authors are grateful to Prof. Kunio Doi for improvement in the English expressions and also in support for guiding the research of young investigators, which is based on the Individual Research Guidance Program established by the Japanese Society of Radiological Technology (JSRT). This manuscript was partly supported by Akiyoshi Ohtsuka Fellowship of the Japanese Society of Radiological Technology for improvement in English expression of a draft version of the manuscript.

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Authors and Affiliations

  1. Division of Clinical Radiology Service, Kyoto University Hospital, 54 Kawaharacho, Syogoin, Sakyo-ku, Kyoto, Kyoto, 606-8507, Japan

    Shuki Maruyama, Yasuhiro Fukushima & Koji Koizumi

  2. Department of Radiological Technology, Radiological Diagnosis, National Cancer Center Hospital, Tokyo, Japan

    Yuta Miyamae

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  1. Shuki Maruyama
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  2. Yasuhiro Fukushima
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  3. Yuta Miyamae
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  4. Koji Koizumi
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Correspondence to Shuki Maruyama.

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Maruyama, S., Fukushima, Y., Miyamae, Y. et al. Usefulness of model-based iterative reconstruction in semi-automatic volumetry for ground-glass nodules at ultra-low-dose CT: a phantom study. Radiol Phys Technol 11, 235–241 (2018). https://doi.org/10.1007/s12194-018-0442-9

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  • DOI: https://doi.org/10.1007/s12194-018-0442-9

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