Abstract
A 44-year-old female presented to her general dentist with the chief complaint of a painful mouth sore of 2 weeks duration. Clinical examination revealed an irregularly shaped ulcer of the buccal and lingual attached gingiva of the anterior mandible. A biopsy was performed and microscopic evaluation revealed histoplasmosis. Histoplasmosis, caused by Histoplasma capsulate, is the most common fungal infection in the United States. Oral lesions of histoplasmosis are generally associated with the disseminated form of histoplasmosis and may present as a fungating or ulcerative lesion of the oral mucosa. The histologic findings and differential diagnosis for oral histoplasmosis are discussed.
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Viswanathan S, Chawla N, D’Cruz A, Kane SV. Head and neck histoplasmosis—a nightmare for clinicians and pathologists! Experience at a Tertiary Referral Cancer Centre. Head Neck Pathol. 2007;1(2):169–72. doi:10.1007/s12105-007-0034-1.
Vidyanath S, Shameena PM, Sudha S, Resmi G Nair. Disseminated histoplasmosis with oral and cutaneous manifestations. J Oral Maxillofac Pathol. 2013;17(1):139–42. doi:10.4103/0973-029X.110722.
Patil K, Mahima VG, Prathibha Rani RM. Oral histoplasmosis. J Indian Soc Periodontol. 2009;13(3):157–9. doi:10.4103/0972-124X.60230.
Brazão-Silva MT, Mancusi GW, Bazzoun FV, Ishisaki GY, Marcucci M. A gingival manifestation of histoplasmosis leading diagnosis. Contemp Clin Dent. 2013;4(1):97–101. doi:10.4103/0976-237X.111621.
Mohammed S, Sinha M, Chavan P, Premalata CS, Shivaprakash MR, Chakrabarti A, Jayshree RS. Oral histoplasmosis masquerading as oral cancer in HIV-infected patient: a case report. Med Mycol Case Rep. 2012;1(1):85–7. doi:10.1016/j.mmcr.2012.09.002.
Akin L, Herford AS, Cicciù M. Oral presentation of disseminated histoplasmosis: a case report and literature review. J Oral Maxillofac Surg. 2011;69(2):535–41. doi:10.1016/j.joms.2010.05.053.
O’Sullivan MV, Whitby M, Chahoud C, Miller SM. Histoplasmosis in Australia: a report of a case with a review of the literature. Aust Dent J. 2004;49(2):94–7.
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Disclaimer The opinions and assertions expressed herein are those of the author and are not to be construed as official or representing the views of the Department of the Navy or the Department of Defense.
Special thank you to Dr. Moris Aynechi of Bakersfield, California for contributing the clinical photos.
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Folk, G.A., Nelson, B.L. Oral Histoplasmosis. Head and Neck Pathol 11, 513–516 (2017). https://doi.org/10.1007/s12105-017-0797-y
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DOI: https://doi.org/10.1007/s12105-017-0797-y