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Role of Histopathology in Differentiating Primary Atrophic Rhinitis from Atrophic Stage of Rhinoscleroma

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Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Atrophic rhinitis (AR) is a chronic debilitating nasal mucosal disease of unknown aetiology and the definitive treatment is still elusive. This often leads to the patient suffering during the entire life span often depleting the individual psychologically. On the contrary, Rhinoscleroma (RS) for which the aetiology is clearly known and is completely curable has atrophic stage which is clinically indistinguishable from AR. Many cases of atrophic stage of RS are undetected and often they end up being treated as AR. This study was conducted to know the role of histopathology and other factors in differentiating AR and Atrophic stage of RS, which can significantly alter the course of treatment and outcome. Forty-five cases of clinically diagnosed AR were included in the study. Punch biopsy of nasal mucosa was obtained from the anterior end of inferior turbinate. Core culture was performed on one sample and histopathological examination for the other sample. Among the 45 patients, 38 (84.44%) of cases were diagnosed to be AR and 7 (15.56%) cases were diagnosed to be RS by histopathology. Core culture of RS subjects showed positive culture for Klebsiella rhinoscleromatis in five subjects (71%). To conclude, AR cases should be confirmed by histopathological examination to rule out RS, for effective management and to prevent complications.

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Funding

This study was self-funded.

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Authors and Affiliations

  1. Department of ENT, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India

    Umesh S. Nagalotimath & Dandinarasaiah Manjunath

  2. Chord Road Hospital and Vikram Hospital, Bangalore, India

    Krishnamurthy Naveen

  3. Department of Pathology, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India

    Rekha B. Puranik

  4. Department of Community Medicine, Sri Devaraj Urs Medical College, Kolar, Karnataka, India

    Mahesh Venkatesha

Authors
  1. Umesh S. Nagalotimath
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  2. Krishnamurthy Naveen
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  3. Rekha B. Puranik
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  4. Dandinarasaiah Manjunath
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  5. Mahesh Venkatesha
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Corresponding author

Correspondence to Krishnamurthy Naveen.

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None of the authors have any conflict of interest

Human and Animal Rights Statement

This article does not contain any studies with animals performed by any of the authors.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Nagalotimath, U.S., Naveen, K., Puranik, R.B. et al. Role of Histopathology in Differentiating Primary Atrophic Rhinitis from Atrophic Stage of Rhinoscleroma. Indian J Otolaryngol Head Neck Surg 69, 62–66 (2017). https://doi.org/10.1007/s12070-017-1053-1

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  • DOI: https://doi.org/10.1007/s12070-017-1053-1

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