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Pentafluorophenylammonium triflate (PFPAT): A new organocatalyst for the one-pot three-component synthesis of α-aminophosphonates

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Abstract

In the presence of a catalytic amount of pentafluorophenylammonium triflate (10 mol %), dimethyl phosphite reacts with imines (generated in situ from aldehydes and amines) to yield the corresponding coupling products in good yield. The organocatalyst is air-stable, cost-effective, easy to handle, and easily removed from the reaction mixtures.

α-Aminophosphonate derivatives were synthesized in excellent yield using PFPAT as an efficient organocatalyst.

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Acknowledgement

This research is supported by the Islamic Azad University, Ayatollah Amoli Branch.

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Authors and Affiliations

  1. Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, PO Box 678, Amol, Iran

    FATEMEH MALAMIRI & SAMAD KHAKSAR

Authors
  1. FATEMEH MALAMIRI
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  2. SAMAD KHAKSAR
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Correspondence to SAMAD KHAKSAR.

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Supplementary information

Supplementary data associated with this article synthesis and NMR spectra can be found in the online version ( www.ias.ac.in/chemsci).

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MALAMIRI, F., KHAKSAR, S. Pentafluorophenylammonium triflate (PFPAT): A new organocatalyst for the one-pot three-component synthesis of α-aminophosphonates. J Chem Sci 126, 807–811 (2014). https://doi.org/10.1007/s12039-014-0636-6

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  • DOI: https://doi.org/10.1007/s12039-014-0636-6

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