Skip to main content

Advertisement

Log in

Spontaneous Regression of Hepatocellular Carcinoma—a Case Report

  • Case Report
  • Published:
Journal of Gastrointestinal Cancer Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

References

  1. Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, et al. GLOBOCAN 2012 v1.1, Cancer incidence and mortality worldwide: IARC CancerBase No. 11 [Internet]. Lyon: International Agency for Research on Cancer; 2014. Available from: http://globocan.iarc.fr, accessed on 01/01/2016.

    Google Scholar 

  2. Everson TC. Spontaneous regression of cancer. Ann N Y Acad Sci. 1964;114(2):721–35.

    Article  Google Scholar 

  3. Chang WY. Complete spontaneous regression of cancer: four case reports, review of literature, and discussion of possible mechanisms involved. Hawaii Med J. 2000;59(10):379–87.

    CAS  PubMed  Google Scholar 

  4. Oquiñena S, Guillen-Grima F, Iñarrairaegui M, et al. Spontaneous regression of hepatocellular carcinoma: a systematic review. Eur J Gastroenterol Hepatol. 2009;21:254–7.

    Article  PubMed  Google Scholar 

  5. Tocci G, Gonte A, Guarascio P, Visco G. Spontaneous remission of hepatocellular carcinoma after massive gastro-intestinal haemorrhage. Br Med J. 1990;300:641–2.

    Article  CAS  Google Scholar 

  6. Breedis C, Young G. The blood supply of neoplasm in the liver. Am J Pathol. 1954;30:969–77.

    CAS  PubMed  PubMed Central  Google Scholar 

  7. Suzuki M, Okazaki N, Yoshino M, et al. Spontaneous regression of a hepatocellular carcinoma—a case report. Hepato-Gastroenterology. 1989;36:160–3.

    CAS  PubMed  Google Scholar 

  8. Iwasaki M, Furuse J, Yoshino M, et al. Spontaneous regression of hepatocellular carcinoma: a case report. Jpn J Clin Oncol. 1997;27:278–81.

    Article  CAS  PubMed  Google Scholar 

  9. Imaoka S, Sasaki Y, Masutani S, et al. Necrosis of hepatocellular carcinoma caused by spontaneously arising arterial thrombus. Hepatogastroenterology. 1994;41:359–62.

    CAS  PubMed  Google Scholar 

  10. Lin TJ, Liao LY, Lin CL, et al. Spontaneous regression of hepatocellular carcinoma: a case report and literature review. Hepatogastroenterology. 2004;51:579–82.

    PubMed  Google Scholar 

  11. Takayasu K, Muramatsu Y, Shima Y, et al. Necrosis of hepatocellular carcinoma as a result of subintimal injury incurred by hepatic angiography: report of two cases. Am J Gastroenterol. 1986;81:979–83.

    CAS  PubMed  Google Scholar 

  12. Ohtani H, Yamazaki O, Matsuyama M, et al. Spontaneous regression of hepatocellular carcinoma: report of a case. Surg Today. 2005;35:1081–6.

    Article  PubMed  Google Scholar 

  13. Cole W. Efforts to explain spontaneous regression of cancer. J Surg Oncol. 1981;17:201–9.

    Article  CAS  PubMed  Google Scholar 

  14. Blondon H, Fritsch L, Cherqui D. Two cases of spontaneous regression of multicentric hepatocellular carcinoma after intra-peritoneal rupture: possible role of immune mechanism. Euro J Gastroenterol Hepatol. 2004;16:1355–9.

    Article  Google Scholar 

  15. Abiru S, Kato Y, Hamasaki K, et al. Spontaneous regression of hepatocellular carcinoma associated with elevated levels of interleukin 18. Am J Gastroenterol. 2002;97:774–5.

    Article  PubMed  Google Scholar 

  16. Heianna J, Miyauchi T, Suzuki T, Ishida H, Hashimoto M, Watarai. Spontaneous regression of multiple lung metastases following regression of hepatocellular carcinoma after transcatheter arterial embolization. A case report. J Hepatogastroenterology. 2007;54(77):1560–2.

    Google Scholar 

  17. Yang SZ, Zhang W, Yuan WS, Dong JH. Recurrence of hepatocellular carcinoma with epithelial-mesenchymal transition after spontaneous regression: a case report. Medicine (Baltimore). 2015;94(28):e1062.

    Article  Google Scholar 

  18. Lim DH, Park KW, Lee SI. Spontaneous complete regression of multiple metastases of hepatocellular carcinoma: a case report. Oncol Lett. 2014;7(4):1225–8.

    PubMed  PubMed Central  Google Scholar 

  19. Yoon HJ, Lim JH. Solid pseudopapillary tumor of the pancreas with hepatic metastasis: spontaneous regression over 10-year follow-up period. Korean J Radiol. 2012;13(5):648–51.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Sasaki T, Fukumori D, Yamamoto K, Yamamoto F, Igimi H, Yamashita Y. Management considerations for purported spontaneous regression of hepatocellular carcinoma: a case report. Case Rep Gastroenterol. 2013;7(1):147–52.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Nakajima T, Moriguchi M, Watanabe T, Noda M, Fuji N, Minami M, et al. Recurrence of hepatocellular carcinoma with rapid growth after spontaneous regression. World J Gastroenterol. 2004;10(22):3385–7.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Alqutub A, Peck D, Marotta P. Spontaneous regression of a large hepatocellular carcinoma: case report. Ger Med Sci. 2011;9 Doc07.

  23. Arora N, Madhusudhana S. Spontaneous regression of hepatocellular cancer: case report and review of literature. Gastrointest Cancer Res. 2011;4:141–3.

    PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mohamed Aftab Alam.

Ethics declarations

Funding

None

Conflict of Interest

The authors declare that they have no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Alam, M.A., Das, D. Spontaneous Regression of Hepatocellular Carcinoma—a Case Report. J Gastrointest Canc 48, 194–197 (2017). https://doi.org/10.1007/s12029-016-9812-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12029-016-9812-x

Keywords

Navigation