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Modifications to the Drug Burden Index Calculation May Limit Interpretation of its Association with Clinical Outcomes in Older Adults

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References

  1. Floroff CK, Slattum PW, Harpe SE, Taylor P, Brophy GM. Potentially inappropriate medication use is associated with clinical outcomes in critically ill elderly patients with neurological injury. Neurocrit Care. 2014. doi:10.1007/s12028-014-9985-8

  2. Hilmer SN, Mager DE, Simonsick EM, Cao Y, Ling SM, Windham BG, Harris TB, Hanlon JT, Rubin SM, Shorr RI, Bauer DC, Abernethy DR. A drug burden index to define the functional burden of medications in older people. Arch Intern Med. 2007;167(8):781–7.

    Article  PubMed  Google Scholar 

  3. Gnjidic D, Cumming RG, Le Couteur DG, Handelsman DJ, Naganathan V, Abernethy DR, Hilmer SN. Drug Burden Index and physical function in older Australian men. Br J Clin Pharmacol. 2009;68(1):97–105.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Wilson NM, Hilmer SN, March LM, Cameron ID, Lord SR, Seibel MJ, Mason RS, Chen JS, Cumming RG, Sambrook PN. Associations between drug burden index and falls in older people in residential aged care. J Am Geriatr Soc. 2011;59(5):875–80.

    Article  PubMed  Google Scholar 

  5. Gnjidic D, Hilmer SN, Blyth FM, Naganathan V, Cumming RG, Handelsman DJ, McLachlan AJ, Abernethy DR, Banks E, Le Couteur DG. High-risk prescribing and incidence of frailty among older community-dwelling men. Clin Pharmacol Ther. 2012;91(3):521–8.

    Article  PubMed  CAS  Google Scholar 

  6. Gnjidic D, Hilmer SN, Hartikainen S, Tolppanen AM, Taipale H, Koponen M, Bell JS. Impact of high risk drug use on hospitalization and mortality in older people with and without Alzheimer’s disease: a national population cohort study. PloS One. 2014;9(1):e83224.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Nishtala PS, Narayan S, Wang T, Hilmer SN. Associations of drug burden index with falls, general practitioner visits, and mortality in older people. Pharmacoepidemiol Drug Saf. 2014. doi:10.1002/pds.3624.

  8. Gnjidic D, Le Couteur DG, Naganathan V, Cumming RG, Creasey H, Waite LM, Sharma A, Blyth FM, Hilmer SN. Effects of drug burden index on cognitive function in older men. J Clin Psychopharmacol. 2012;32(2):273–7.

    Article  PubMed  Google Scholar 

  9. Wilson NM, Hilmer SN, March LM, Cameron ID, Lord SR, Seibel MJ, Sambrook PN. Associations between drug burden index and physical function in older people in residential aged care facilities. Age Ageing. 2010;39(4):503–7.

    Article  PubMed  Google Scholar 

  10. Wilson NM, Hilmer SN, March LM, Chen JS, Gnjidic D, Mason RS, Cameron ID, Sambrook PN. Associations between drug burden index and mortality in older people in residential aged care facilities. Drugs Aging. 2012;29(2):157–65.

    Article  PubMed  Google Scholar 

  11. Hilmer SN, Gnjidic D, Abernethy DR. Drug Burden Index for International Assessment of the Functional Burden of Medications in Older People. J Am Geriatr Soc. 2014;62(4):791–2.

    Article  PubMed  Google Scholar 

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Correspondence to Lisa Kouladjian.

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Kouladjian, L., Gnjidic, D., Chen, T.F. et al. Modifications to the Drug Burden Index Calculation May Limit Interpretation of its Association with Clinical Outcomes in Older Adults. Neurocrit Care 21, 365–366 (2014). https://doi.org/10.1007/s12028-014-0006-8

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  • DOI: https://doi.org/10.1007/s12028-014-0006-8

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