Skip to main content
Log in

CORR Insights®: Does Vitamin D Improve Osteoarthritis of the Knee: A Randomized Controlled Pilot Trial

  • CORR Insights®
  • Published:
Clinical Orthopaedics and Related Research®

The Original Article was published on 01 August 2013

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Bellamy N, Campbell J, Welch V, Gee T, Bourne R, Wells GA. Intraarticular corticosteroid for treatment of osteoarthritis of the knee: The Cochrane Collaboration. John Wiley & Sons, Ltd.; 2009.

  2. Felson DT. The verdict favors nonsteroidal antiinflammatory drugs for treatment of osteoarthritis and a plea for more evidence on other treatments. Arthritis Rheum. 2001;44:1477–1480.

    Article  PubMed  CAS  Google Scholar 

  3. Felson DT, Niu J, Clancy M, Aliabadi P, Sack B, Guermazi A, Hunter DJ, Amin S, Rogers G, Booth SL. Low levels of vitamin D and worsening of knee osteoarthritis: results of two longitudinal studies. Arthritis Rheum. 2007;56:129–136.

    Article  PubMed  CAS  Google Scholar 

  4. Glover TL, Goodin BR, Horgas AL, Kindler LL, King CD, Sibille KT, Peloguin CA, Riley JL 3rd, Staud R, Bradley LA, Fillingim RB. Vitamin D, race, and experimental pain sensitivity in older adults with knee osteoarthritis. Arthritis Rheum. 2012;64:3926–3935.

    Article  PubMed  CAS  Google Scholar 

  5. McAlindon TE, Felson DT, Zhang Y, Hannan MT, Aliabadi P, Weissman B, Rush D, Wilson PW, Jacques P. Relation of dietary intake and serum levels of vitamin D to progression of osteoarthritis of the knee among participants in the Framingham Study. Ann Intern Med. 1996;125:353–359.

    Article  PubMed  CAS  Google Scholar 

  6. McAlindon T, Lavalley M, Schneider E, Nuite M, Lee JY, Price LL, Lo G, Dawson-Hughes B. Effect of vitamin D supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: a randomized controlled trial. JAMA. 2013;309:155–162.

    Article  PubMed  CAS  Google Scholar 

  7. Nguyen US, Zhang Y, Zhu Y, Niu J, Zhang B, Felson DT. Increasing prevalence of knee pain and symptomatic knee osteoarthritis: survey and cohort data. Ann Intern Med. 2011;155:725–732.

    Article  PubMed  Google Scholar 

  8. Tetlow LC, Woolley DE. Expression of vitamin D receptors and matrix metalloproteinases in osteoarthritic cartilage and human articular chondrocytes in vitro. Osteoarthritis Cartilage. 2001;9:423–431.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to David T. Felson MD, MPH.

Additional information

This CORR Insights® is a commentary on the article “Does Vitamin D Improve Osteoarthritis of the Knee: A Randomized Controlled Pilot Trial” by Sanghi and colleagues available at: DOI: 10.1007/s11999-013-3201-6.

The author certifies that he, or a member of his immediate family, has no funding or commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article.

All ICMJE Conflict of Interest Forms for authors and Clinical Orthopaedics and Related Research ® editors and board members are on file with the publication and can be viewed on request.

The opinions expressed are those of the writers, and do not reflect the opinion or policy of CORR ® or the Association of Bone and Joint Surgeons®.

This CORR Insights® comment refers to the article available at DOI: 10.1007/s11999-013-3201-6.

About this article

Cite this article

Felson, D.T. CORR Insights®: Does Vitamin D Improve Osteoarthritis of the Knee: A Randomized Controlled Pilot Trial. Clin Orthop Relat Res 471, 3563–3564 (2013). https://doi.org/10.1007/s11999-013-3269-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11999-013-3269-z

Keywords

Navigation