Abstract
In the United States analgesic-overuse headache is often caused by butalbital-containing analgesics. These agents can cause physical and psychological dependency, and dangerous withdrawal syndromes. Butalbital-containing analgesics have already been banned in several European countries. They are proven effective in tension-type headache, but not in migraine; there are many alternative treatments for migraine and tension-type headache. In the 20 years since analgesic overuse headache was widely recognized, butalbital overuse has remained distressingly common. It is time to ban these agents.
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Young, W.B., Siow, H.C. Should butalbital-containing analgesics be banned? Yes.. Current Science Inc 6, 151–155 (2002). https://doi.org/10.1007/s11916-002-0012-y
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DOI: https://doi.org/10.1007/s11916-002-0012-y