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Eliminating Infections in the ICU: CLABSI

  • Sepsis and ICU (L Napolitano, Section Editor)
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Abstract

Central line-associated bloodstream infections (CLABSI) are one of the leading causes of death in the USA and around the world. As a preventable healthcare-associated infection, they are associated with significant morbidity and excess costs to the healthcare system. Effective and long-term CLABSI prevention requires a multifaceted approach, involving evidence-based best practices coupled with effective implementation strategies. Currently recommended practices are supported by evidence and are simple, such as appropriate hand hygiene, use of full barrier precautions, avoidance of femoral lines, skin antisepsis, and removal of unnecessary lines. The most successful and sustained improvements in CLABSI rates further utilize an adaptive component to align provider behaviors with consistent and reliable use of evidence-based practices. Great success has been achieved in reducing CLABSI rates in the USA and elsewhere over the past decade, but more is needed. This article aims to review the initiatives undertaken to reduce CLABSI and summarizes the sentinel and recent literature regarding CLABSI and its prevention.

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Peter Pronovost, Asad Latif, and Muhammad Sohail Halim have no relevant disclosures to report.

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  1. Department of Anesthesiology and Critical Care Medicine, Armstrong Institute for Patient Safety and Quality, Johns Hopkins Medicine, 600 North Wolfe Street, Meyer 297-A, Baltimore, MD, 21287, USA

    Asad Latif & Peter J. Pronovost

  2. Aga Khan University Hospital, Karachi, Pakistan

    Muhammad Sohail Halim

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  1. Asad Latif
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  2. Muhammad Sohail Halim
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  3. Peter J. Pronovost
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Correspondence to Asad Latif.

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Latif, A., Halim, M.S. & Pronovost, P.J. Eliminating Infections in the ICU: CLABSI. Curr Infect Dis Rep 17, 35 (2015). https://doi.org/10.1007/s11908-015-0491-8

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