Current Bladder Dysfunction Reports

, Volume 8, Issue 1, pp 62–68

Obesity and the Overactive Bladder

Overactive Bladder (A Klausner, Section Editor)

DOI: 10.1007/s11884-012-0172-5

Cite this article as:
Fry, C.H. Curr Bladder Dysfunct Rep (2013) 8: 62. doi:10.1007/s11884-012-0172-5


Obesity (BMI greater than 30 kg.m-2) and overweight (BMI greater 25-30 kg.m-2) are associated with an increased prevalence of pelvic floor disorders, including urinary incontinence and overactive bladder (OAB) syndrome. A positive association between obesity and OAB is present in women, although it is more difficult to demonstrate in men. OAB may result from several obesity-related conditions including the mechanical effect of increased body mass on the bladder, a result of type-II diabetes or the presence of metabolic syndrome. The underlying metabolic defects of the latter two conditions in generating OAB are discussed. Finally the involvement of endothelial dysfunction as a cause of OAB is considered, as this pathology is a result of several obesity-related conditions.


Overactive bladderObesityOverweightBMIStress urinary incontinenceLUTSType-II diabetesMetabolic syndromeHypoxiaReactive oxygen species

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.The Institute of Biosciences and MedicineUniversity of SurreyGuildfordUK