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Health-related quality of life is associated with physical activity levels among colorectal cancer survivors: a longitudinal, 3-year study of the PROFILES registry

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Abstract

Purpose

The present study aims to examine the longitudinal relation between physical activity (PA) and health-related quality of life (HRQoL) among colorectal cancer (CRC) survivors.

Methods

Individuals diagnosed with CRC between 2000 and 2009 as registered by the Dutch population-based Eindhoven Cancer Registry, and who were eligible for the study, received a questionnaire on three time points with 1-year intervals. Generalized linear mixed models were used to estimate the independent effects of PA on HRQoL over time.

Results

Response rates were 73 % (n = 2625), 83 % (n = 1643), and 82 % (n = 1458) at T1, T2, and T3, respectively. PA behavior was relatively stable over time with 82 % of the patients meeting the Dutch PA guidelines (at least 150 min of moderate to vigorous PA per week) at all assessment periods. Multivariate analyses showed that patients who met the PA guidelines scored, on average, 13.7 points higher on the global quality of life, 26.0 on physical, 24.2 on role, 9.0 on cognitive, 10.4 on emotional, and 14.8 on social functioning over time compared to patients not meeting the guidelines (interindividual effects; all p < 0.01). Small intraindividual effects were found for physical (2.9) and role functioning (4.0) and global quality of life (2.1), indicating that patients who went from not meeting to meeting the guidelines over time improved on these scales (p < 0.05).

Conclusion

There is a substantial positive association between PA and HRQoL, which is consistent over time for CRC survivors >2 years since diagnosis.

Implications for Cancer Survivors

Our results underline the importance to focus upon training in survivorship care and strategies to get inactive cancer survivors physically active.

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Conflict of interest

Olga Husson, Floortje Mols, Nicole Ezendam, Goof Schep, and Lonneke van de Poll-Franse declare that they have no conflict of interest.

Author information

Authors and Affiliations

  1. CoRPS—Center of Research on Psychology in Somatic Diseases, Department of Medical and Clinical Psychology, Tilburg University, Warandelaan 2, PO Box 90153, 5000 LE, Tilburg, The Netherlands

    Olga Husson, Floortje Mols, Nicole P. M. Ezendam & Lonneke V. van de Poll-Franse

  2. Comprehensive Cancer Centre the Netherlands (CCCN), Eindhoven Cancer Registry, Eindhoven, The Netherlands

    Olga Husson, Floortje Mols, Nicole P. M. Ezendam & Lonneke V. van de Poll-Franse

  3. Department of Sports Medicine, Maxima Medical Centre, Veldhoven, The Netherlands

    Goof Schep

Authors
  1. Olga Husson
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  2. Floortje Mols
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  3. Nicole P. M. Ezendam
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  4. Goof Schep
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  5. Lonneke V. van de Poll-Franse
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Corresponding author

Correspondence to Olga Husson.

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This manuscript has been prepared in accordance with the style of the journal, and all authors have approved of its contents. This manuscript is not being considered for publication elsewhere, and the findings of this manuscript have not been previously published.

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Husson, O., Mols, F., Ezendam, N.P.M. et al. Health-related quality of life is associated with physical activity levels among colorectal cancer survivors: a longitudinal, 3-year study of the PROFILES registry. J Cancer Surviv 9, 472–480 (2015). https://doi.org/10.1007/s11764-014-0423-x

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  • DOI: https://doi.org/10.1007/s11764-014-0423-x

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