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Outcomes of surgical aortic valve replacement using Carpentier-Edwards PERIMOUNT bioprosthesis series in elderly patients with severe aortic valve stenosis: a retrospective cohort study

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Abstract

Objective

We sought to compare the outcomes of Carpentier-Edwards PERIMOUNT (CEP), Magna and Magna Ease valves in Japanese elderly patients with severe aortic valve stenosis (AS).

Methods

We retrospectively identified 136 patients (mean age 76.61 ± 5.5 years old) who had undergone isolated surgical aortic valve replacement (SAVR) using CEP, Magna, and Magna Ease valves at a single institution, from January 2001 to December 2013. We compared the valves according to their survival rates, freedom from major adverse cardiovascular and cerebrovascular events (MACCE), and durability and hemodynamic performance by echocardiographic data.

Results

The thirty-day mortality after isolated SAVR in all the valve groups was “zero”. The differences among the three groups in terms of survival rates, freedom from MACCE at 2 years, durability and hemodynamic performance of the valves by echocardiographic data was not statistically significant.

Conclusion

All CEP, Magna and Magna Ease valves seemed to be similarly useful in Japanese elderly patients with severe AS. Our data did not clearly support the superiority of one valve over another. A longer follow-up period might be necessary to compare the durability and hemodynamic performance of these valves with more certainty.

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Authors and Affiliations

  1. Department of Cardiovascular Surgery, Teine Keijinkai Hospital, 12-1-40, Maeda 1-jo, Teine-ku, Sapporo, Hokkaido, 006-8555, Japan

    Naritomo Nishioka, Akira Yamada, Kosuke Ujihira, Yutaka Iba, Ryushi Maruyama, Eiichiro Hatta, Yoshihiko Kurimoto & Katsuhiko Nakanishi

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  1. Naritomo Nishioka
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  2. Akira Yamada
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  3. Kosuke Ujihira
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  4. Yutaka Iba
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  5. Ryushi Maruyama
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  6. Eiichiro Hatta
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  7. Yoshihiko Kurimoto
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  8. Katsuhiko Nakanishi
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Correspondence to Naritomo Nishioka.

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All of the authors declare that they had no competing interests related to this study.

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Nishioka, N., Yamada, A., Ujihira, K. et al. Outcomes of surgical aortic valve replacement using Carpentier-Edwards PERIMOUNT bioprosthesis series in elderly patients with severe aortic valve stenosis: a retrospective cohort study. Gen Thorac Cardiovasc Surg 64, 728–734 (2016). https://doi.org/10.1007/s11748-016-0698-0

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  • DOI: https://doi.org/10.1007/s11748-016-0698-0

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