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Douleur et thermorégulation. La thermorégulation chez l’animal

Pain and thermoregulation. Thermoregulation in animals

  • Mise Au Point / Update
  • Published:
Douleur et Analgésie

Résumé

Les interactions entre thermorégulation et nociception s’exercent sur deux fronts, périphérique et central. Sur le front périphérique, plusieurs éléments sont à prendre en compte, qui sont des sources importantes de variation pour les « tests de douleur ». En outre, les structures cérébrales qui contrôlent la thermorégulation et la transmission spinale des messages nociceptifs sont très intimement liées sur le plan anatomique, notamment en ce qui concerne les voies effectrices descendantes, issues de la région bulbaire rostroventrale. Nous faisons le point sur l’acquisition des informations thermiques et sur les réponses de l’organisme qu’elles suscitent par l’intermédiaire des « thermoeffecteurs ». Nous décrivons les mécanismes centraux qui déterminent ces réponses qui, après intégration dans l’hypothalamus, sont déterminées par la mise en route de neurones sympathiques prémoteurs situés dans la région bulbaire rostroventrale et dont les axones cheminent dans les funiculus dorsolatéraux (DLF). Ainsi mis en place, ces éléments nous permettront d’envisager dans un prochain article les conséquences fonctionnelles des interactions entre thermorégulation et nociception qui s’exercent centralement.

Abstract

Interactions between thermoregulation and nociception are carried out on two fronts–peripheral and central. On the peripheral, a number of elements should be taken into account. These are significant sources of variation for “pain tests”. Furthermore, the brain structures which control thermoregulation and the spinal transmission of nociceptive messages are closely linked in the human anatomy, especially with regard to descending effector pathways, arising from the rostroventral bulbar region. We are reviewing the acquisition of thermal information and the body’s responses arising through the use of “thermoeffectors”. We will detail the central mechanisms which determine these responses which, after integration of the hypothalamus, are determined by the introduction of sympathetic premotor neurons located in the rostroventral bulbar region, including the axons routing through the dorsolateral funiculus (DLF). Thus implemented, in an upcoming article these elements enable us to envisage the functional consequences of interactions between thermoregulation and nociception carried out centrally.

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  1. Sorbonne universités, université Pierre-et-Marie-Curie, Faculté de médecine, F-75013, Paris, France

    N. El Bitar & D. Le Bars

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Nous dédions cet article à notre collègue et ami Bernard Pollin qui nous a quittés brutalement. Depuis de nombreuses années, sa contribution à notre travail d’équipe a été essentielle et déterminante. Nous lui en serons reconnaissants à jamais.

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El Bitar, N., Le Bars, D. & Neurosciences Paris-Seine. Douleur et thermorégulation. La thermorégulation chez l’animal. Douleur analg 28, 186–205 (2015). https://doi.org/10.1007/s11724-015-0437-9

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