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Can CT angiography reconstructed from CT perfusion source data on a 320-section volume CT scanner replace conventional CT angiography for the evaluation of intracranial arteries?

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Abstract

Purpose

To compare conventional CT angiography (CTA) and CTA reconstructed from CT perfusion source data (perfusion CTA) acquired on a 320-section CT scanner for the evaluation of intracranial arteries.

Materials and methods

Our study included 7 patients who had undergone trapping of an intracranial aneurysm and placement of a bypass. All underwent conventional and perfusion CTA and digital subtraction angiography (DSA). Using DSA as the gold standard, 2 radiologists evaluated 10 arterial segments on conventional and perfusion CTA images. On a 4-point scale they independently scored the image quality and vascular visualization of the intracranial arteries on the conventional and perfusion CTA images. The effective radiation dose to each patient was also recorded.

Results

A total of 65 arterial segments without apparent abnormalities were assessed. While the mean image quality score tended to be slightly higher for conventional than perfusion CTA, there was no significant difference. The effective dose for perfusion and conventional CTA with unenhanced CT was 4.2 mSv and 3.1 mSv, respectively, for all patients.

Conclusion

For the evaluation of intracranial arteries using DSA as the gold standard, perfusion CTA yields image quality and vascular visualization similar to conventional CTA at an acceptable radiation dose.

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Abbreviations

CTA:

CT angiography

CTP:

CT perfusion

CBF:

Cerebral blood flow

CBV:

Cerebral blood volume

MTT:

Mean transit time

DSA:

Digital subtraction angiography

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Conflict of interest

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Authors and Affiliations

  1. Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan

    Masafumi Kidoh, Seitaro Oda, Daisuke Utsunomiya, Yasuhiko Iryo, Minako Azuma, Eri Hayashida, Takeshi Nakaura & Yasuyuki Yamashita

  2. Department of Neurosurgery, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan

    Takayuki Kawano, Shigetoshi Yano, Hideo Nakamura & Keishi Makino

  3. Department of Radiology, School of Medicine, Miyazaki University, Miyazaki, Japan

    Toshinori Hirai

Authors
  1. Masafumi Kidoh
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  2. Toshinori Hirai
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  3. Seitaro Oda
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  4. Daisuke Utsunomiya
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  5. Takayuki Kawano
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  6. Shigetoshi Yano
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  7. Hideo Nakamura
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  8. Keishi Makino
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  9. Yasuhiko Iryo
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  10. Minako Azuma
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  11. Eri Hayashida
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  12. Takeshi Nakaura
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  13. Yasuyuki Yamashita
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Corresponding author

Correspondence to Masafumi Kidoh.

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Kidoh, M., Hirai, T., Oda, S. et al. Can CT angiography reconstructed from CT perfusion source data on a 320-section volume CT scanner replace conventional CT angiography for the evaluation of intracranial arteries?. Jpn J Radiol 33, 353–359 (2015). https://doi.org/10.1007/s11604-015-0429-y

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  • DOI: https://doi.org/10.1007/s11604-015-0429-y

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