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Follow-up MR findings of spinal foraminal nerve sheath tumors after stereotactic irradiation

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Japanese Journal of Radiology Aims and scope Submit manuscript

Abstract

Purpose

The purpose of this study was to investigate follow-up MR findings of spinal foraminal nerve sheath tumors after stereotactic irradiation.

Materials and methods

Thirty-five foraminal nerve sheath tumors in 28 patients who underwent stereotactic radiosurgery (SRS) (n = 28) or stereotactic radiotherapy (SRT) (n = 7) were included. The MR images were reviewed to identify serial changes in tumor volume and intratumoral necrosis. Growth and shrinkage were defined as volume changes of ±19.7 % or more; stability was within ±19.7 %. Transient swelling was defined as shrinkage preceded by significant growth. A tumor with shrinkage or stability was regarded as tumor control.

Results

Of 35 tumors, 16 (46 %) were stable, 14 (40 %) shrunk, and 5 (14 %) grew. Transient swelling was seen for 13 (37 %) lesions. Newly developed intratumoral necrosis was observed for 19 (54 %) of 35 tumors and was significantly associated with transient swelling (p = 0.039) and with tumor control (p = 0.017). SRS was not significantly associated with transient swelling.

Conclusion

In follow-up MR images of spinal foraminal nerve sheath tumors after stereotactic irradiation, newly developed intratumoral necrosis and transient swelling were often seen. Intratumoral necrosis was associated with transient swelling and tumor control.

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Acknowledgments

This work was supported by a grant from Inje University in 2012.

Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Radiology, Inje University Ilsan Paik Hospital, College of Medicine, 2240, Daehwa-dong, Ilsanseo-gu, Goyang-si, Gyeonggi-do, 411-706, Korea

    Hyo Jin Kang, Yoon Joon Hwang, Yong Hoon Kim, Su Young Kim & Byung Hoon Lee

  2. Department of Neurosurgery, Inje University Ilsan Paik Hospital, College of Medicine, 2240, Daehwa-dong, Ilsanseo-gu, Goyang-si, Gyeonggi-do, 411-706, Korea

    Moon-Jun Sohn

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  1. Hyo Jin Kang
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  2. Yoon Joon Hwang
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  3. Yong Hoon Kim
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  4. Su Young Kim
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Corresponding author

Correspondence to Yoon Joon Hwang.

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Kang, H.J., Hwang, Y.J., Kim, Y.H. et al. Follow-up MR findings of spinal foraminal nerve sheath tumors after stereotactic irradiation. Jpn J Radiol 31, 192–196 (2013). https://doi.org/10.1007/s11604-012-0169-1

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  • DOI: https://doi.org/10.1007/s11604-012-0169-1

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