Abstract
Optimal management of radiotherapy for prostate cancer patients has become a major concern for physicians in Japan. We reviewed published reports identifying the differences in the patterns of care for prostate cancer patients treated with radical external beam radiotherapy in Japan, Germany, and the United States. The reports indicate that Japanese patients have more advanced primary disease than patients in Germany or the United States. These patient characteristics for Japan and the United States have been almost unchanged for several years. Regarding radiotherapy, conformal radiotherapy was less frequently administered to patients in Japan than patients in Germany or the United States, and the total radiation dose was higher in Germany and the United States than in Japan. Concerning changes in trends in the patterns of radiotherapy, the percentage of patients treated with higher dose levels in the United States has rapidly increased, whereas the percentage of patients receiving these dose levels in Japan has remained extremely low. On the other hand, hormonal therapy has been used more frequently in Japan than in Germany or the United States. These findings indicate that patient characteristics and patterns of care for prostate cancer in Japan are considerably different from those in Germany or the United States.
Similar content being viewed by others
References
Yoshimi I, Mizuno S. Cancer statistics mortality trends of prostate cancer in Japan: 1960–2000. Jpn J Clin Oncol 2003;33:367.
Hanks GE, Coia LR, Curry J. Patterns of care studies: past, present and future. Semin Radiat Oncol 1997;7:97–100.
Owen JB, Sedransk J, Pajak TF. National averages for process and outcome in radiation oncology: methodology of the patterns of care study. Semin Radiat Oncol 1997;7:101–107.
Teshima T. Patterns of care study in Japan. Jpn J Clin Oncol 2005;35:497–506.
Teshima T, Abe M, Ikeda H, Hanks GE, Owen JB, Yamada S, et al. Patterns of care study of radiation therapy for cervix cancer in Japan: the influence of the stratification of institution on the process. Jpn J Clin Oncol 1998;28:388–395.
Teshima T, Abe M, Ikeda H, Hanks GE, Owen JB, Hiraoka M, et al. Patterns of care study of radiation therapy for esophageal cancer in Japan: influence of the stratification on the process. Jpn J Clin Oncol 1998;28:308–313.
Nakamura K, Teshima T, Takahashi Y, Imai A, Koizumi M, Mitsuhashi M, et al. Radical radiotherapy for prostate cancer in Japan: a patterns of care study report. Jpn J Clin Oncol 2003;33:122–126.
Nakamura K, Teshima T, Takahashi Y, Imai A, Koizumi M, Mitsuhashi M, et al. Radiotherapy for localized hormonerefractory prostate cancer in Japan. Anticancer Res 2004;24:3141–3145.
Nakamura K, Ogawa K, Yamamoto Y, Sasaki T, Koizumi M, Teshima T, et al. Trends in the practice of radiotherapy for localized prostate cancer in Japan: a preliminary patterns of care study report. Jpn J Clin Oncol 2003;33:527–532.
Ogawa K, Nakamura K, Onishi H, Sasaki T, Koizumi M, Shioyama Y, et al. Radical external beam radiotherapy for clinically localized prostate cancer in Japan: changing trends in the patterns of care process survey between 1996–1998 and 1999–2001. Anticancer Res 2005;25:3507–3511.
Ogawa K, Nakamura K, Onishi H, Sasaki T, Koizumi M, Shioyama Y, et al. Radical external beam radiotherapy for prostate cancer in Japan: results of the 1999–2001 patterns of care process survey. Jpn J Clin Oncol 2006;36:40–45.
Ogawa K, Nakamura K, Onishi H, Sasaki T, Koizumi M, Shioyama Y, et al. Radical external beam radiotherapy for clinically localized prostate cancer in Japan: differences in the patterns of care between Japan and the United States. Anticancer Res 2006;26:575–580.
Ogawa K, Nakamura K, Onishi H, Koizumi M, Sasaki T, Araya M, et al. Influence of age on the pattern and outcome of external beam radiotherapy for clinically localized prostate cancer. Anticancer Res 2006;26:1319–1325.
Vordermark D, Marold D, Wirth S, Keilholz L, Pfandner K, Schimpke T, et al. Patterns of care in the radiotherapy of prostate cancer in northern Bavaria 1998–2000. Strahlenther Onkol 2007;183:314–320.
Zelefsky MJ, Moughan J, Owen J, Zeitman AL, Roach M 3rd, Hanks GE. Changing trends in national practice for external beam radiotherapy for clinically localized prostate cancer: 1999 patterns of care survey for prostate cancer. Int J Radiat Oncol Biol Phys 2004;59:1053–1061.
Hanks GE, Hanlon AL, Schultheiss TE, Pinover WH, Movsas B, Epstein BE, et al. Dose escalation with 3D conformal treatment: five year outcomes, treatment optimization, and future directions. Int J Radiat Oncol Biol Phys 1998;41:501–510.
Zelefsky MJ, Leibel SA, Gaudin PB, Kutcher GJ, Fleshner NE, Venkatramen ES, et al. Dose escalation with three-dimensional conformal radiation therapy affects the outcomes in prostate cancer. Int J Radiat Oncol Biol Phys 1998;41:491–500.
Sumi M, Ikeda H, Tokuuye K, Kagami Y, Murayama S, Tobisu K, et al. The external radiotherapy with threedimensional conformal boost after the neoadjuvant androgen suppression for patients with locally advanced prostatic carcinoma. Int J Radiat Oncol Biol Phys 2000;48:519–528.
Zietman AL. Radiation therapy or prostatectomy: an old conflict revisited in the PSA era; a radiation oncologist’s view-point. Semin Radiat Oncol 1998;8:81–86.
Hanks GE, Schultheiss TE, Hanlon AL, Hunt M, Lee WR, Epstein BE, et al. Optimization of conformal radiation treatment of prostate cancer: report of a dose escalation study. Int J Radiat Oncol Biol Phys 1997;37:543–550.
Takara K. The origins and development of public health in Japan. In: Detels R, McEwen J, Omenn GS (eds) Oxford textbook of public health, 3rd edition. Vol 1: The scope of public health. New York: Oxford University Press; 1997. p. 55–77.
Bolla M, Gonzalez D, Warde P, Dubois JB, Mirimanoff RO, Storme G, et al. Improved survival in patients with locally advanced prostate cancer treated with radiotherapy and goserelin. N Engl J Med 1997;337:295–300.
Pilepich MV, Krall JM, al-Sarraf M, John MV, Doggett RL, Lawton CA, et al. Androgen deprivation with radiation therapy compared with radiation therapy alone for locally advanced prostatic carcinoma: a randomized comparative trial of the Radiation Therapy Oncology Group. Urology 1995;45:616–623.
Zietman A, Moughan J, Owen J, Hanks G. The patterns of case survey of radiation therapy in localized prostate cancer: similarities between the practice nationally and in minorityrich areas. Int J Radiat Oncol Biol Phys 2001;50:75–80.
Author information
Authors and Affiliations
Consortia
Corresponding author
About this article
Cite this article
Ogawa, K., Nakamura, K., Sasaki, T. et al. Radical external beam radiotherapy for prostate cancer in Japan: differences in the patterns of care among Japan, Germany, and the United States. Radiat Med 26, 57–62 (2008). https://doi.org/10.1007/s11604-007-0195-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11604-007-0195-6