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Renal function and diffusion-weighted imaging: a new method to diagnose kidney failure before losing half function

  • ABDOMINAL RADIOLOGY
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Abstract

Aim

To diagnose earlier kidney failure, we investigated renal functions with diffusion-weighted imaging (DWI).

Methods

We evaluated the DWI of 62 patients with chronic kidney disease (CKD) and compared it with creatinine clearance provided by daily urine collection. The apparent diffusion coefficient (ADC) values were compared with the five stages of CKD.

Results

For each stage of CKD, the ADC values were found to be significantly different (p < 0.01) and allowed the differentiation of stage 1 of the disease from the other stages.

Conclusion

Renal ADC values show a significant correlation with the clinical stages of CKD. DWI may detect renal failure prior to a rise in creatinine.

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Authors and Affiliations

  1. Department of Nephrology, Istanbul Research and Training Hospital, Istanbul, Turkey

    Türker Emre

  2. Department of Radyology, Istanbul Research and Training Hospital, Istanbul, Turkey

    Özgür Kiliçkesmez & Atılay Büker

  3. Department of Biochemistry, Istanbul Research and Training Hospital, Istanbul, Turkey

    Berrin Berçik İnal

  4. Fatih Private Hemodialysis Unite, Istanbul, Turkey

    Hüseyin Doğan

  5. Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Istanbul University, Fatih, Istanbul, Turkey

    Tevfik Ecder

Authors
  1. Türker Emre
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  2. Özgür Kiliçkesmez
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  3. Atılay Büker
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  4. Berrin Berçik İnal
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  5. Hüseyin Doğan
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  6. Tevfik Ecder
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Correspondence to Türker Emre.

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The authors declare that they have no conflict of interest.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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Informed consent was obtained from all individual participants included in the study.

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Emre, T., Kiliçkesmez, Ö., Büker, A. et al. Renal function and diffusion-weighted imaging: a new method to diagnose kidney failure before losing half function. Radiol med 121, 163–172 (2016). https://doi.org/10.1007/s11547-015-0579-0

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  • DOI: https://doi.org/10.1007/s11547-015-0579-0

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