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Bacterial persistence

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  • Special Topic Biophysical Chemistry
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Abstract

Although bacterial persistence was first observed in 1944, its underlying mechanism is just beginning to be understood and many fundamental questions remain. In this review, we summarize studies in order to chart the full map of bacterial persistence. Because persistence significantly contributes to disease recalcitrance, we also elucidate the probable relationships between bacterial persistence and prolonged chronic infections, with some comments on future research directions and therapeutic strategies.

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Authors and Affiliations

  1. Biodynamic Optical Imaging Center (BIOPIC), School of Life Sciences, Peking University, Beijing, 100871, China

    YunXiao Liu, Jin Yang, ZhiLun Zhao, YingYing Pu & Fan Bai

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  1. YunXiao Liu
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  2. Jin Yang
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  3. ZhiLun Zhao
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  4. YingYing Pu
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  5. Fan Bai
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Correspondence to YingYing Pu or Fan Bai.

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These authors contributed equally to this work

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Liu, Y., Yang, J., Zhao, Z. et al. Bacterial persistence. Sci. China Chem. 57, 1625–1633 (2014). https://doi.org/10.1007/s11426-014-5245-1

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