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Dysosesquiflorins A and B, sesquiterpenoids from Dysoxylum densiflorum

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Abstract

Two new aromadendrane sesquiterpenoids, dysosesquiflorins A and B (1 and 2), were isolated from Dysoxylum densiflorum bark, and their structures were elucidated on the basis of NMR spectroscopic data. These dysosesquiflorins showed in vitro cytotoxic activity against several cancer cell lines.

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Acknowledgment

This work was supported by Grants in-Aid for Scientific Research from JSPS.

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Authors and Affiliations

  1. Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41, Shinagawa-Ku, Tokyo, 142-8501, Japan

    Alfarius E. Nugroho, Rio Sugiura, Takanori Momota, Yusuke Hirasawa, Chin Piow Wong, Toshio Kaneda & Hiroshi Morita

  2. Department of Chemistry, Faculty of Science, University Malaya, 50603, Kuala Lumpur, Malaysia

    A. Hamid A. Hadi

Authors
  1. Alfarius E. Nugroho
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  2. Rio Sugiura
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  3. Takanori Momota
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  4. Yusuke Hirasawa
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  5. Chin Piow Wong
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  6. Toshio Kaneda
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  7. A. Hamid A. Hadi
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  8. Hiroshi Morita
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Correspondence to Hiroshi Morita.

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Nugroho, A.E., Sugiura, R., Momota, T. et al. Dysosesquiflorins A and B, sesquiterpenoids from Dysoxylum densiflorum . J Nat Med 69, 411–415 (2015). https://doi.org/10.1007/s11418-015-0888-6

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  • DOI: https://doi.org/10.1007/s11418-015-0888-6

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