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Preclinical Studies on Tumor-Specific Fluorescent Targeting Agents: the Need for a Gold Standard of Tumor Localization

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References

  1. Day KE, Sweeny L, Kulbersh B, Zinn KR, Rosenthal EL (2013) Preclinical comparison of near-infrared-labeled cetuximab and panitumumab for optical imaging of head and neck squamous cell carcinoma. Mol Imaging Biol. doi:10.1007/s11307-013-0652-9

    PubMed  Google Scholar 

  2. Keereweer S, Mol IM, Vahrmeijer AL et al (2012) Dual wavelength tumor targeting for detection of hypopharyngeal cancer using near-infrared optical imaging in an animal model. Int J Cancer 131:1633–1640

    Article  CAS  PubMed  Google Scholar 

  3. Heath CH, Deep NL, Sweeny L, Zinn KR, Rosenthal EL (2012) Use of panitumumab-IRDye800 to image microscopic head and neck cancer in an orthotopic surgical model. Ann Surg Oncol 19:3879–3887

    Article  PubMed Central  PubMed  Google Scholar 

  4. Zhu B, Wu G, Robinson H et al (2013) Tumor margin detection using quantitative NIRF molecular imaging targeting EpCAM validated by far red gene reporter iRFP. Mol Imaging Biol. doi:10.1007/s11307-013-0637-8

    Google Scholar 

  5. Gerlinger M, Rowan AJ, Horswell S et al (2012) Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. New Engl J Med 366:883–892

    Article  CAS  PubMed  Google Scholar 

  6. Marusyk A, Almendro V, Polyak K (2012) Intra-tumour heterogeneity: a looking glass for cancer? Nat Rev Cancer 12:323–334

    Article  CAS  PubMed  Google Scholar 

  7. Keereweer S, Van Driel PB, Snoeks TJ et al (2013) Optical image-guided cancer surgery: challenges and limitations. Clin Cancer Res. doi:10.1158/1078-0432

    PubMed  Google Scholar 

  8. Braakhuis BJ, Tabor MP, Kummer JA, Leemans CR, Brakenhoff RH (2003) A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implications. Cancer Res 63:1727–1730

    CAS  PubMed  Google Scholar 

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The authors declare that they have no conflict of interest.

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Correspondence to Stijn Keereweer.

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This paper presents a comment on the study entitled “Preclinical Comparison of Near-Infrared-Labeled Cetuximab and Panitumumab for Optical Imaging of Head and Neck Squamous Cell Carcinoma” by Katherine Day, Larissa Sweeny, Brian Kulbersh, Kurt R. Zinn and Eben L. Rosenthal, MIB-13-071-Mar.

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Keereweer, S., Van Driel, P.B.A.A. & Lowik, C.W.G.M. Preclinical Studies on Tumor-Specific Fluorescent Targeting Agents: the Need for a Gold Standard of Tumor Localization. Mol Imaging Biol 16, 10–12 (2014). https://doi.org/10.1007/s11307-013-0684-1

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  • DOI: https://doi.org/10.1007/s11307-013-0684-1

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