Abstract
Recently, gemycircularviruses have been found in humans and various species of animals. Here, a novel gemycircularvirus named Ch-zjrat-01 from blood samples of experimental rats was characterized. The novel gemycircularvirus encodes two major proteins, including a capsid protein (Cap) and a replication-associated protein (Rep). Phylogenetic analysis based on the amino acid sequence of Rep indicated that Ch-zjrat-01 clusters with two gemycircularviruses discovered from bird (KF371635) and mosquito (HQ335086), sharing 48.7 and 49.4 % sequence identities with them, respectively.
References
K. Rosario, A. Dayaram, M. Marinov, J. Ware, S. Kraberger, D. Stainton, M. Breitbart, A. Varsani, Diverse circular ssDNA viruses discovered in dragonflies (Odonata: Epiprocta). J. Gen. Virol. 93, 2668–2681 (2012)
X. Yu, B. Li, Y. Fu, D. Jiang, S.A. Ghabrial, G. Li, Y. Peng, J. Xie, J. Cheng, J. Huang, X. Yi, A geminivirus-related DNA mycovirus that confers hypovirulence to a plant pathogenic fungus. Proc. Natl. Acad. Sci. USA 107, 8387–8392 (2010)
A. Sikorski, M. Massaro, S. Kraberger, L.M. Young, D. Smalley, D.P. Martin, A. Varsani, Novel myco-like DNA viruses discovered in the faecal matter of various animals. Virus Res. 177, 209–216 (2013)
J.M.A. Van den Brand, M. van Leeuwen, C.M. Schapendonk, J.H. Simon, B.L. Haagmans, A.D.M.E. Osterhaus, S.L. Smits, Metagenomic analysis of the viral flora of pine marten and European badger feces. J. Virol. 86, 2360–2365 (2012)
A. Dayaram, K.A. Potter, R. Pailes, M. Marinov, D.D. Rosenstein, A. Varsani, Identification of diverse circular single-stranded DNA viruses in adult dragonflies and damselflies (Insecta: Odonata) of Arizona and Oklahoma, USA. Infect. Genet. Evol. 30, 278–287 (2015)
S. Kraberger, G.R. Argüello-Astorga, L.G. Greenfield, C. Galilee, D. Law, D.P. Martin, A. Varsani, Characterisation of a diverse range of circular replication-associated protein encoding DNA viruses recovered from a sewage treatment oxidation pond. Infect. Genet. Evol. 31, 73–86 (2015)
A. Dayaram, A. Opong, A. Jäschke, J. Hadfield, M. Baschiera, R.C.J. Dobson, S.K. Offei, D.N. Shepherd, D.P. Martin, A. Varsani, Molecular characterisation of a novel cassava associated circular ssDNA virus. Virus Res. 166, 130–135 (2012)
Z. Du, Y. Tang, S. Zhang, X. She, G. Lan, A. Varsani, Z. He, Identification and molecular characterization of a single-stranded circular DNA virus with similarities to Sclerotinia sclerotiorum hypovirulence-associated DNA virus 1. Arch. Virol. 159, 1527–1531 (2014)
S. Kraberger, K. Farkas, P. Bernardo, C. Booker, G.R. Argüello-Astorga, F. Mesléard, D.P. Martin, P. Roumagnac, A. Varsani, Identification of novel Bromus- and Trifolium-associated circular DNA viruses. Arch. Virol. 160, 1303–1311 (2015)
I. Lamberto, K. Gunst, H. Müller, H. Zur Hausen, E.-M. de Villiers, Mycovirus-like DNA virus sequences from cattle serum and human brain and serum samples from multiple sclerosis patients. Genome Announc. (2014). doi:10.1128/genomeA.00848-14
T.G. Phan, D. Mori, X. Deng, S. Rajindrajith, U. Ranawaka, T.F. Fan Ng, F. Bucardo-Rivera, P. Orlandi, K. Ahmed, E. Delwart, Small circular single stranded DNA viral genomes in unexplained cases of human encephalitis, diarrhea, and in untreated sewage. Virology 482, 98–104 (2015)
K. Tamura, D. Peterson, N. Peterson, G. Stecher, M. Nei, S. Kumar, MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 28, 2731–2739 (2011)
P. Zawar-Reza, G.R. Argüello-Astorga, S. Kraberger, L. Julian, D. Stainton, P.A. Broady, A. Varsani, Diverse small circular single-stranded DNA viruses identified in a freshwater pond on the McMurdo Ice Shelf (Antarctica). Infect. Genet. Evol. 26, 132–138 (2014)
E. Delwart, L. Li, Rapidly expanding genetic diversity and host range of the Circoviridae viral family and other Rep encoding small circular ssDNA genomes. Virus Res. 164, 114–121 (2012)
L. Li, T. Shan, O.B. Soji, M.M. Alam, T.H. Kunz, S.Z. Zaidi, E. Delwart, Possible cross-species transmission of circoviruses and cycloviruses among farm animals. J. Gen. Virol. 92, 768–772 (2011)
G. Loconsole, P. Saldarelli, H. Doddapaneni, V. Savino, G.P. Martelli, M. Saponari, Identification of a single-stranded DNA virus associated with citrus chlorotic dwarf disease, a new member in the family Geminiviridae. Virology 432, 162–172 (2012)
A. Sikorski, J. Kearvell, S. Elkington, A. Dayaram, G.R. Argüello-Astorga, A. Varsani, Novel ssDNA viruses discovered in yellow-crowned parakeet (Cyanoramphus auriceps) nesting material. Arch. Virol. 158, 1603–1607 (2013)
T.F.F. Ng, D.L. Willner, Y.W. Lim, R. Schmieder, B. Chau, C. Nilsson, S. Anthony, Y. Ruan, F. Rohwer, M. Breitbart, Broad surveys of DNA viral diversity obtained through viral metagenomics of mosquitoes. PLoS One 6, e20579 (2011)
Acknowledgments
This work was partly supported by the National Natural Science Foundation of China No. 31302107, the Natural Science Foundation of Jiangsu Province No. BK2012289, and China Postdoctoral Special Science Foundation No. 2015T80503.
Author information
Authors and Affiliations
Corresponding author
Additional information
Edited by Keizo Tomonaga.
Rights and permissions
About this article
Cite this article
Li, W., Gu, Y., Shen, Q. et al. A novel gemycircularvirus from experimental rats. Virus Genes 51, 302–305 (2015). https://doi.org/10.1007/s11262-015-1238-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11262-015-1238-1