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Identification of some main Streptococcus iniae associated proteins: relationship

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An Erratum to this article was published on 22 March 2017

Abstract

The surface-associated proteins play a key role in bacterial physiology and pathogenesis, and are the major targets in the development of new vaccines. These proteins contribute to the adaptation of bacteria to different hosts and environments. To study differences at the genomic level, we first sequenced the whole genome of Streptococcus iniae from fish (IUSA-1 strain) and compared it to Streptococcus iniae from human (9117 strain), revealing a high similitude between both strains. To gain further insights into host- and environment-specific differences, we then studied proteins in silico and by High Performance Liquid Chromatography. This approach successfully identified 54 secreted and surface proteins, including several proteins involved in cell wall synthesis and transport of solutes, as well as proteins with yet unknown function. These proteins highlight as interesting targets for further investigation in the interaction between Streptococcus iniae and its environment. Results reported in this study have shown a first analysis about the predicted and experimental associated proteins of Streptococcus iniae isolated from two different hosts: human and fish.

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Acknowledgements

We would like to thank Dr. MY Mistou for his assistance and support during the experiment and analysis of samples and Dr. Melody N. Neely for kindly providing the S. iniae 9117 strain.

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Authors and Affiliations

  1. Institut National de Recherche Halieutique (INRH), M’diq, Morocco

    Fatima El Aamri

  2. Unidad Asociada de Biomedicina IIBM CSIC, University of Las Palmas de Gran Canaria, Las Palmas, Spain

    José Ángel Guillén

  3. University Institute of Animal Health, University of Las Palmas de Gran Canaria, 35413, Arucas, Spain

    Daniel Padilla, Félix Acosta & Fernando Real

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  1. Fatima El Aamri
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  2. José Ángel Guillén
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  3. Daniel Padilla
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  5. Fernando Real
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Correspondence to Daniel Padilla.

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An erratum to this article is available at http://dx.doi.org/10.1007/s11259-017-9688-7.

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El Aamri, F., Guillén, J.Á., Padilla, D. et al. Identification of some main Streptococcus iniae associated proteins: relationship. Vet Res Commun 41, 85–95 (2017). https://doi.org/10.1007/s11259-017-9675-z

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