Abstract
The association of antiphospholipid antibodies and Takayasu arteritis is very rare and few cases have been reported in the past. Though Takayasu arteritis patients were treated in the past with stenting, there have been no reports of patients with this association being treated with carotid stenting. We present here a young Bahraini female with Takayasu arteritis, primary antiphospholipid antibody syndrome and methylene tetrahydrofolate reductase C677T and A1298C polymorphism, who was treated with carotid stenting and anticoagulants.
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References
Vanoli M, Bacchiani G, Origgi L, Scorza R. Takayasu’s arteritis: A changing disease. J Nephrol 2001;14:497–505.
Yokoi K, Hosoi E, Akaike M, Shigekiyo T, Saito S. Takayasu’s arteritis associated with antiphospholipid antibodies. Report of two cases. Angiology 1996;47:315–319.
Jean-Jaquet RS. Takayasu’s arteritis and antiphospholipid antibody syndrome in pregnancy. Philipp J Obstet Gynecol 1998;22:99–106.
Nava A, Senecal JL, Banales JL, Raymond I, Reyes PA. Absence of antiphopholipid/co-factor antibodies in Takayasu’s arteritis. Int J Cardiol 2000;75:S99–S104.
Gupta A, Chandra N, Kler TS. Aortoarteritis with systemic lupus erythematosus and secondary antiphospholipid antibody syndrome: A rare association. Indian Heart J 2002;54:301–303.
Ishikawa K. Diagnostic approach and proposed criteria for the clinical diagnosis of Takayasu’s arteriopathy. J Am Coll Cardiol 1988;12:964–972.
Sharma BK, Iliskovic NS, Singal PK. Takayasu’s arteritis may be underdiagnosed in North America. Can J Cardiol 1995;11:311–316.
Levine JS, Branch DW, Rauch J. The Antiphospholipid syndrome. N Engl J Med 2002;346:752–762.
Nityanand S. Autoantibodies against cardiolipin and endothelial cells in Takayasu’s arteritis: Prevalence and isotype distribution. Br J Rheumatol 1997;36:923–924.
Sattar MA, White AG, Eklof B, Fenech FF. Takayasu’s disease in Arabs. Postgrad Med J 1985;61:387–390.
Casas JP, Hingorani AD, Bautista LE, Sharma P. Meta-analysis of genetic studies in ischemic stroke: Thirty two genes involving approximately 18,000 cases and 58,000 controls. Arch Neurol 2004;61:1652–1662.
Kim NK, Choi BO. MTHFR A1298C gene polymorphism: Independent risk factor for ischemic stroke? Korean Neurol Assoc J 2003;21:606–613.
Saxe PA, Altman RD. Takayasu’s arteritis syndrome associated with systemic lupus erythematosus. Semin Arthritis Rheum 1992;21:295–305.
Bali HK, Bhargava MM, Bhatta YK, Sandhu MS. Single stage bilateral common carotid artery stenting in a patient of Takayasu arteritis. Neurol India 2001;49:87–90.
Sharma BK, Jain S, Bali HK, Jain A, Kumari S. A follow-up study of balloon Int J Cardiol 2000;75:S147–152.
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Jishi, A.A., Krishnan, P.R. & Almawi, W.Y. Takayasu Arteritis with High Titre of Antiphospholipid Antibodies and MTHFR Polymorphism. J Thromb Thrombolysis 20, 47–50 (2005). https://doi.org/10.1007/s11239-005-2459-2
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DOI: https://doi.org/10.1007/s11239-005-2459-2