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Optimization of the Extraction of Biologically Active Substances from Yellow Toadflax (Linaria vulgaris) Herb

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Pharmaceutical Chemistry Journal Aims and scope

Optimization of the extraction of biologically active substances from yellow toadflax produced data indicating that the active principles were extracted most completely from raw material if vacuum-filtration extraction was used. The process was carried out with heating at 42°C, infusion for 40 min, and solid:liquid phase ratio 1:10. The yield of extracted flavonoids under these conditions was 96.7% of the total content in the raw material; of iridoids, 93.8%. The selected parameters could be considered optimal and recommended as industrial processing parameters for further production of extracts and their integration into medical practice.

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Acknowledgments

The work was supported by the Governor of Perm Territory and the Ministry of Education of Perm Territory.

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Authors and Affiliations

  1. Perm State Pharmaceutical Academy, Perm, 614990, Russia

    O. V. El’kina, N. I. Shramm, E. I. Molokhova & V. M. Petrichenko

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  1. O. V. El’kina
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  2. N. I. Shramm
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  3. E. I. Molokhova
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  4. V. M. Petrichenko
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Deceased (V. M. Petrichenko)

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 48, No. 4, pp. 32 – 34, April, 2014.

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El’kina, O.V., Shramm, N.I., Molokhova, E.I. et al. Optimization of the Extraction of Biologically Active Substances from Yellow Toadflax (Linaria vulgaris) Herb. Pharm Chem J 48, 273–275 (2014). https://doi.org/10.1007/s11094-014-1092-9

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  • DOI: https://doi.org/10.1007/s11094-014-1092-9

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