Skip to main content
SpringerLink
Log in

Weight matrix analysis for back reflection continuous wave diffuse optical tomography (CWDOT) systems: translational method

  • Published:
Optical and Quantum Electronics Aims and scope Submit manuscript

Abstract

Back reflection continuous wave diffuse optical tomography (CWDOT) systems use forward model photon fluence rate distributions for inverse problem solution to be able to reconstruct images. Forward model weight functions are also known as photon fluence rate distributions inside the homogenous media. The linearized equation systems are used for CWDOT imaging. To be able to recover the unknown delta absorption coefficients over background inside the homogenous media linearized equation system has to be solved. In this work the forward model weight matrix functions have been calculated according to the photon distribution of radiative transport equation in theoretical physics. After the forward model is set, the mathematical inverse problem solution methods have to be applied. In literature, the solution of linearized CWDOT equation systems are nonlinear methods but they have never been popular. The main goal of this study is to be able to show alternative weight matrix generation method. The weight matrix generation is very important for linearized CWDOT systems. The Monte Carlo (MC) simulations have been used to create the weight matrix by using the radiation transport problem solution via Rytov or Born approximation. The photon is sent into the tissue, the step distances of each photons are computed and the scattering angles of photons have to be known. It is calculated by occurrence probability for each voxel by the Henyey-Greenstein phase function. The generated MC simulation data is migrated from the simulation environment to the image reconstruction algorithm environment. The weight matrix is successively generated by explained translational method.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  • Feng, S., Zeng, F., Chance, B.: Monte Carlo simulations of photon migration path distributions in multiple scattering media. Proc. SPIE 1888, 78–89 (1993)

    Article  ADS  Google Scholar 

  • Jacques, S.L., Wang, L.H.: Monte Carlo modeling of light transport in tissues. In: Welch, A.J., Van Gemert, M.J.C. (eds.) Optical thermal response of laser irradiated tissue, pp. 73–100. Plenum Press, New York (1995)

    Chapter  Google Scholar 

  • Jacques, S.L.: Modeling tissue optics using Monte Carlo modeling: a tutorial. In: Proceedings of SPIE 6854, Optical Interactions with Tissue and Cells XIX, 68540T, (2008). doi: 10.1117/12.776997

  • Jacques, S.L.: Spectral imaging and analysis to yield tissue optical properties. J. Innov. Opt. Health Sci. 2(2), 1–7 (2009)

    Article  MathSciNet  Google Scholar 

  • Jacques, S.L., Kazanci, H.O.: Diffuse light tomography to detect blood vessels using tikhonov regularization. Biophotonics internet invited lecture, Optical Technologies in Biophysics & Medicine XVI Saratov, Russia (2014)

  • Kazanci, H.O., Canpolat, M.: Mathematical method for diffuse optical tomography imaging: a research study. El-Cezerî J. Sci. Eng. 1(3), 40–48 (2014)

    Google Scholar 

  • Kazanci, H.O., Canpolat, M.: Depth normalization algorithm for continuous wave reflectance diffuse optical tomography system. El-Cezerî J. Sci. Eng. 2(1), 40–46 (2015a)

    Google Scholar 

  • Kazanci, H.O., Canpolat, M.: Continuous wave diffuse optical tomography system with high resolution current to voltage analog digital converter. El-Cezerî J. Sci. Eng. 2(1), 68–77 (2015b)

    Google Scholar 

  • Kazanci, H.O., Mercan, T., Canpolat, M.: Design and evaluation of a reflectance diffuse optical tomography system. Opt. Quant. Electron. 47(2), 257–265 (2015)

    Article  Google Scholar 

  • Prahl, S.A., Keijzer, M., Jacques, S.L., Welch, A.J.: A monte carlo model of light propagation in tissue. SPIE Proc. Dosim. Laser Radiat. Med. Biol. 5, 102–111 (1989)

    Google Scholar 

  • Wang, L.H., Jacques, S.L.: Optimized radial and angular positions in Monte Carlo modeling. Med. Phys. 21(7), 1081–1083 (1994)

    Article  Google Scholar 

  • Wang, L.H., Jacques, S.L., Zheng, L.Q.: Monte Carlo modeling of photon transport in multi-layered tissues. Comput. Methods Programs Biomed. 47(2), 131–146 (1995)

    Article  Google Scholar 

  • Wang, L.H., Jacques, S.L., Zheng, L.Q.: Convolution for responses to a finite diameter photon beam incident on multi-layered tissues. Comput. Methods Programs Biomed. 54(3), 141–150 (1997)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biomedical Engineering, Clinical Engineering, Faculty of Engineering, Akdeniz University, Antalya, 07058, Turkey

    Huseyin Ozgur Kazanci

Authors
  1. Huseyin Ozgur Kazanci
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Huseyin Ozgur Kazanci.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kazanci, H.O. Weight matrix analysis for back reflection continuous wave diffuse optical tomography (CWDOT) systems: translational method. Opt Quant Electron 47, 3847–3853 (2015). https://doi.org/10.1007/s11082-015-0252-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11082-015-0252-9

Keywords

Search

Navigation