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Synthesis of nanosized carbonated apatite by a modified Pechini method: hydroxyapatite nucleation from a polymeric matrix

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Abstract

Pechini method is a materials synthesis method based on the preparation of a polymeric matrix. The advantage of this method is the ability to obtain materials with different particle sizes depending on the synthesis condition with a homogeneous distribution. In this work, carbonated hydroxyapatite (c-OHAp) nanoparticles were obtained by a modified Pechini method. To obtain the polymeric precursor of the c-OHAp, the polymeric matrix was prepared through a polyesterification reaction between citric acid and ethylene-glycol. Adding calcium hydroxide and ortophosphoric acid in aqueous solutions, raising the temperature up to 140 °C/2 h and keeping constant the pH at 8. The polymeric matrix was calcinated at different ranges of temperature from 200 to 600 °C in order to obtain the c-OHAp powder. The results show the presence of c-OHAp a as unique phase. The thermal analysis indicates that the c-OHAp phase was obtained at 600 °C. The particle size of the obtained material was <50 nm.

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Acknowledgments

The authors thanks to UNAM-DGAPA for postdoctoral scholarship supporting to NVB during the course of this study. We appreciate the technical support from S. Tehuacanero Núñez, P. Mexia Hernández This study was partially conducted with the financial support granted by DGAPA-UNAM through projects IN106710 and IN213912, by IPN through SIP project 20130452 and by CICYT, Spain through project MAT2010-18155.

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Authors and Affiliations

  1. Laboratorio de Bioingeniería de Tejidos; División de Estudios de Posgrado e Investigación, Facultad de Odontología, UNAM, Circuito Exterior s/n, 04510, Coyoacán, Mexico, D.F., Mexico

    N. Vargas-Becerril & M. A. Alvarez-Perez

  2. Departamento de Ingeniería en Metalurgia y Materiales ESIQIE-IPN, Unidad Profesional Adolfo López Mateos, 07738, Mexico, D.F., Mexico

    L. Téllez-Jurado

  3. Instituto de Física, UNAM, Circuito de la Investigación s/n, 04510, Coyoacán, Mexico, D.F., Mexico

    J. Reyes-Gasga

  4. Instituto de Ciencia y Tecnología de Polímeros, Departamento de Nanomateriales Poliméricos y Biomateriales, ICTP-CSIC, Juan de la Cierva No. 3, Madrid, 28006, Spain

    L. M. Rodríguez-Lorenzo

  5. GBP, CIBER-BBN, Madrid, Spain

    N. Vargas-Becerril, L. Téllez-Jurado, J. Reyes-Gasga, M. A. Alvarez-Perez & L. M. Rodríguez-Lorenzo

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  1. N. Vargas-Becerril
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Correspondence to N. Vargas-Becerril.

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Vargas-Becerril, N., Téllez-Jurado, L., Reyes-Gasga, J. et al. Synthesis of nanosized carbonated apatite by a modified Pechini method: hydroxyapatite nucleation from a polymeric matrix. J Sol-Gel Sci Technol 72, 571–580 (2014). https://doi.org/10.1007/s10971-014-3478-2

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  • DOI: https://doi.org/10.1007/s10971-014-3478-2

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