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Synthesis of Phytonanocomposite of Zinc Oxide by Ixora coccinea Linn for Cancer Treatment

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Abstract

Bioactive peptides from Ixora coccinea Linn flowers have been reported to have anticancer activity against various cancer cells. Zinc oxide nanoparticle is the promising metal nanoparticle for anticancer applications. In the present work, ZnO was synthesized using I. coccinea Linn flower extract. The synthesized ZnO nanoparticle was found as phytonanocomposite of ZnO nanoparticle and bioactive components. The synthesized ZnO phytonanocomposite was confirmed using UV Spectroscopic analysis with maximum wavelength at 357.6 nm. The presence of bioactive peptides in the nanophytocomposite was confirmed using FT-IR analysis with strong peaks at 3402 and 1629 cm−1. The particle size and surface characteristics of bioactive phytonanocomposite of ZnO was studied using Scanning Electron Microscope. The anticancer activity of zinc oxide nanocomposite of I. coccinea Linn flower extract was found to be efficient on MCF-7 cell line.

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Authors and Affiliations

  1. Department of Biotechnology, St. Joseph’s College of Engineering, Chennai, 600 119, India

    G. Baskar, A. Gurugulladevi, T. Nishanthini, Bikku George Garrick & R. Aiswarya

  2. Department of Chemical Engineering, College of Engineering Studies, University of Petroleum and Energy Studies, Dehradun, 248 007, India

    M. Gopinath

Authors
  1. G. Baskar
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  2. A. Gurugulladevi
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  3. T. Nishanthini
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  4. Bikku George Garrick
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  5. R. Aiswarya
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  6. M. Gopinath
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Correspondence to G. Baskar.

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Baskar, G., Gurugulladevi, A., Nishanthini, T. et al. Synthesis of Phytonanocomposite of Zinc Oxide by Ixora coccinea Linn for Cancer Treatment. J Inorg Organomet Polym 26, 876–880 (2016). https://doi.org/10.1007/s10904-016-0382-y

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  • DOI: https://doi.org/10.1007/s10904-016-0382-y

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