Abstract
Latinos in the US are disproportionately affected by chronic liver disease, which is the sixth most common cause of death among this group. In Mexico, cirrhosis and other liver diseases are the fourth leading cause of general mortality. The objective of this study was to contrast the liver disease risk factors, knowledge, and prevention practices reported among separate samples of Mexicans living in Los Angeles, CA and in Cuernavaca, Mexico. We assessed the prevalence of specific risk factors (body mass index, waist circumference, and alcohol consumption), the level of knowledge about liver disease in general, hepatitis B (HBV), and hepatitis C (HCV), as well as prevention activities such as screening and vaccination. Data were collected from in-person interviews and anthropometric measures obtained from Mexican adults aged 18–70 years. Chi-square and t tests were used to compare the results between groups. Numerous similarities were observed in the bi-national samples, including high prevalence of obesity, abdominal obesity, and high levels of alcohol consumption. Most participants in both countries recognized that excessive alcohol consumption is a risk factor for liver disease, but only 60% correctly identified hepatitis C, being overweight or obese, or having diabetes as risk factors. Few participants reported having been screened for HBV or HCV, vaccinated for HBV, or having the intention of getting screened for HBV or HCV. US participants reported significantly higher levels of prevention activities and screening intentions than those in Mexico. Identifying the specific risk factors, levels of knowledge and prevention activities that affect specific racial/ethnic populations is important in order to effectively target efforts to prevent liver disease.
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Younossi, Z. M., & Stepanova, M. (2010). Hepatitis C virus infection, age, and Hispanic ethnicity increase mortality from liver cancer in the United States. Clinical Gastroenterology and Hepatology, 8(8), 718–723.
Vega, W. A., Rodriguez, M. A., & Gruskin, E. (2009). Health disparities in the Latino population. Epidemiologic Reviews, 31, 99–112.
National Center for Health Statistics. Health, U.S. (2010). Leading causes of death by race/ethnicity in 1980 and 2007. Hyattsville, MD, 2011. Available at: http://www.cdc.gov/nchs/data/hus/hus10.pdf. Accessed June 21, 2011.
Browning, J. D., Szczepaniak, L. S., Dobbins, R., et al. (2004). Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology, 40(6), 1387–1395.
U.S. Cancer Statistics Working Group. (2010). United States cancer statistics: 1999–2007 incidence and mortality web-based report. Atlanta: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute 2010. Available at: http://apps.nccd.cdc.gov/uscs/. Accessed June 21, 2011.
North American Association of Central Cancer Registries (NAACCR). (2010). Cancer in North America: 2003–2007 Volume 1: Combined cancer incidence for the United States and Canada. Available at: http://www.naaccr.org/DataandPublications/CINAPubs.aspx. Accessed June 21, 2011.
Sistema Nacional de Información en Salud. (2011). Principales causas de mortalidad general, 2008. Available at: http://sinais.salud.gob.mx/mortalidad/. Accessed June 21, 2011.
Haber, P. S., Warner, R., Seth, D., Gorrell, M. D., & McCaughan, G. (2003). Pathogenesis and management of alcoholic hepatitis. Clinical Gastroenterology and Hepatology, 18(12), 1332–1344.
Hashimoto, E., Taniai, M., Kaneda, H., et al. (2004). Comparison of hepatocellular carcinoma patients with alcoholic liver disease and nonalcoholic steatohepatitis. Alcoholism, Clinical and Experimental Research, 28, 164S–168S.
Alter, M. J. (2003). Epidemiology and prevention of hepatitis B. Seminars in Liver Disease, 23(1), 39–46.
Lauer, G. M., & Walter, B. D. (2001). Hepatitis C virus infection. The New England Journal of Medicine, 345(1), 41–52.
Festi, D., Coleccia, A., Sacco, T., Bondi, M., Roda, E., & Marchesini, G. (2004). Hepatic steatosis in obese patients: Clinical aspects and progressive significance. Obesity Reviews, 5(1), 27–42.
Farrell, G. C., & Larter, C. Z. (2006). Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology, 43, S99–S112.
El-Serag, H. B., Tran, T., & Everhart, J. E. (2004). Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma. Gastroenterology, 126, 460–468.
Ruhl, C. E., & Everhart, J. E. (2004). Epidemiology of nonalcoholic fatty liver. Clinics in Liver Disease, 8(3), 501–519.
Schindhelm, R. K., Diamant, M., Dekker, J. M., et al. (2006). Alanine aminotransferase as a marker of non-alcoholic fatty liver disease in relation to type 2 diabetes mellitus and cardiovascular disease. Diabetes Metabolism Research and Reviews, 22(6), 437–443.
Slonim, A. B., Roberto, A. J., Downing, C. R., et al. (2005). Adolescents’ knowledge, beliefs, and behaviors regarding hepatitis B: Insights and implications for programs targeting vaccine-preventable diseases. The Journal of Adolescent Health, 36(3), 178–186.
Rhodes, S. D., & Diclemente, R. J. (2003). Psychosocial predictors of hepatitis B vaccination among young African-American gay men in the deep south. Sexually Transmitted Diseases, 30(5), 449–454.
Jenkins, C. N., McPhee, S. J., Wong, C., Nguyen, T., & Euler, G. L. (2000). Hepatitis B immunization coverage among Vietnamese-American children 3 to 18 years old. Pediatrics, 106(6), E78.
Heimer, R., Clair, S., Grau, L. E., Bluthenthal, R. N., Marshall, P. A., & Singer, M. (2002). Hepatitis-associated knowledge is low and risks are high among HIV-aware injection drug users in three US cities. Addiction, 97(10), 1277–1287.
Kwiatkowski, C. F., Fortuin, C. K., & Booth, R. E. (2002). The association between knowledge of hepatitis C virus status and risk behaviors in injection drug users. Addiction, 97(10), 1289–1294.
Kermode, M., Jolley, D., Langkham, B., Thomas, M. S., & Crofts, N. (2005). Occupational exposure to blood and risk of bloodborne virus infection among health care workers in rural north Indian health care settings. American Journal of Infection Control, 33(1), 34–41.
Shehab, T. M., Sonnad, S., Gebremariam, A., & Schoenfeld, P. (2002). Knowledge of hepatitis C screening and management by internal medicine residents: Trends over 2 years. The American Journal of Gastroenterology, 97(5), 1216–1222.
Taylor, V. M., Choe, J. H., Yasui, Y., Li, L., Burke, N., & Jackson, C. (2005). Hepatitis B awareness, testing and knowledge among Vietnamese American men and women. Journal of Community Health, 30(6), 477–490.
Nguyen, T. T., Taylor, V., Chen, M. S., Jr, Bastani, R., Maxwell, A. E., & McPhee, S. J. (2007). Hepatitis B awareness, knowledge, and screening among Asian Americans. Journal of Cancer Education, 22(4), 266–272.
Wu, C. A., Lin, S. Y., So, S. K., & Chang, E. T. (2007). Hepatitis B and liver cancer knowledge and preventive practices among Asian Americans in the San Francisco Bay Area, California. Asian Pacific Journal of Cancer Prevention, 8(1), 127–134.
Taylor, V. M., Jackson, C., Chan, N., Kuniyuki, A., & Yasui, Y. (2002). Hepatitis B: Knowledge and practices among Cambodian American women in Seattle, Washington. Journal of Community Health, 27(3), 151–163.
Williams, G. D., Dufour, M., & Bertolucci, D. (1986). Drinking levels, knowledge, and associated characteristics, 1985 NHIS findings. Public Health Report, 101(6), 593–598.
Leung, C. M., Lai, L. S. W., Wong, W. H., et al. (2009). Non-alcoholic fatty liver disease: An expanding problem with low levels of awareness in Hong Kong. Journal of Gastroenterology and Hepatology, 24(11), 1786–1790.
Soto-Salgado, M., Suárez, E., Ortiz, A. P. et al. (2010). Knowledge of viral hepatitis among puerto rican adults: Implications for prevention. Journal of Community Health, 36(4), 565–573.
Bastani, R., Glenn, B. A., Maxwell, A. E., & Jo, A. M. (2007). Hepatitis B testing for liver cancer control among Korean Americans. Ethnicity and Disease, 17(2), 365–373.
Bastani, R., Glenn, B. A., Taylor, V. M., et al. (2010). Integrating theory into community interventions to reduce liver cancer disparities: The health behavior framework. Preventive Medicine, 50(1–2), 63–67.
Grundy, S. M., Brewer, H. B., Jr, Cleeman, J. L., Smith, S. C., Jr, & Lenfant, C. (2004). American Heart Association; National Heart, Lung, and Blood Institute. definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition. Circulation, 109(3), 433–438.
Centers for Disease Control and Prevention. (2007). Surveillance for certain health behaviors among states and selected local areas, behavioral risk factor surveillance system, U.S. 2010. In Surveillance Summaries, December 2007. MMWR 2007; 59.
Flores, Y. N., Yee, H. F., Jr, Leng, M., et al. (2008). Risk factors for chronic liver disease in Blacks, Mexican Americans, and Whites in the United States: results from NHANES IV, 1999–2004. The American Journal of Gastroenterology, 103(9), 2231–2238.
Méndez-Sánchez, N., García-Villegas, E., Merino-Zeferino, B., et al. (2010). Liver diseases in Mexico and their associated mortality trends from 2000 to 2007: A retrospective study of the nation and the federal states. Annals of Hepatology, 9(4), 428–438.
Roesch-Dietlen, F., Dorantes-Cuéllar, A., Carrillo-Toledo, M. G., et al. (2006). Frequency of NAFLD in a group of patients with metabolic syndrome in Veracruz, Mexico. Revista de gastroenterología de México, 71(4), 446–452.
Buffington, J., Damon, S., Moyer, L., & Culver, D. (2000). Racial differences in knowledge regarding hepatitis C virus infection. Journal of the American Medical Association, 284(13), 1651–1652.
Greby, S. M., Lu, P., Euler, G., Williams, W. W., & Singleton, J. A. (2009). 2009 Adult vaccination coverage, NHIS national center for immunization and respiratory diseases, immunization services division. Available at: http://www.cdc.gov/vaccines/stats-surv/nhis/2009-nhis.htm. Accessed July 26, 2011.
U.S. Census 2010. (2011). 2010 Census shows America’s diversity. Available at: http://2010.census.gov/news/releases/operations/cb11-cn125.html. Accessed June 21, 2011.
U.S. Census 2010. (2011). Data for the State of California. Available at: http://2010.census.gov/news/releases/operations/cb11-cn68.html. Accessed June 21, 2011.
Borjas, G. J. (2007). Mexican migration to the United States. Chicago: University of Chicago Press.
U.S. Census Bureau. (2011) Top ten countries with which the U.S. trades. Available at: http://www.census.gov/foreign-trade/top/dst/current/balance.html. Accessed July 26, 2011.
Acknowledgments
This research was supported by a grant from the UCLA Jonsson Cancer Center Foundation awarded to Dr. Flores (grant number 04084543), and a research grant from the Coordinación de Investigación en Salud of the Mexican Institute of Social Security (IMSS) awarded to Dr. Flores. Additional support was provided by the Unidad de Investigación Epidemiológica y en Servicios de Salud, Morelos (IMSS) and the UCLA Kaiser Permanente Center for Health Equity. The authors would like to thank Cindy Chang and Oyuki Liviett Rueda for providing statistical support.
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The authors have no conflicts of interest to disclose.
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Flores, Y.N., Lang, C.M., Salmerón, J. et al. Risk Factors for Liver Disease and Associated Knowledge and Practices Among Mexican Adults in the US and Mexico. J Community Health 37, 403–411 (2012). https://doi.org/10.1007/s10900-011-9457-4
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DOI: https://doi.org/10.1007/s10900-011-9457-4