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45S5 Bioglass®–MWCNT composite: processing and bioactivity

  • Biomaterials Synthesis and Characterization
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Abstract

Multi-walled carbon nanotube (MWCNT)–Bioglass (BG) matrix composite was fabricated using a facile and scalable aqueous colloidal processing method without using any surfactants followed by spark plasma sintering (SPS) consolidation. The individual MWCNTs were initially uniformly dispersed in water and then entirely immobilized on the BG particles during the colloidal processing, avoiding their common re-agglomeration during the water-removal and drying step, which guaranteed their uniform dispersion within the dense BG matrix after the consolidation process. SPS was used as a fast sintering technique to minimise any damage to the MWCNT structure during the high-temperature consolidation process. The electrical conductivity of BG increased by 8 orders of magnitude with the addition of 6.35 wt% of MWCNTs compared to pure BG. Short-duration tests were used in the present study as a preliminary evaluation to understand the effect of incorporating MWCNTs on osteoblast-like cells. The analysed cell proliferation, viability and phenotype expression of MG-63 cells showed inhibition on 45S5 Bioglass®–MWCNT composite surfaces.

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Acknowledgments

The authors would like to thank European Union’s Seventh Framework Program managed by REA-Research Executive Agency http://ec.europa.eu/research/rea (Marie Curie Action, GlaCERCo GA 264526) and International Center for Young Scientists (ICYS) of National Institute for Materials Science (NIMS), Tsukuba, Japan for their support and funding for this research. Prof. M.J. Reece would like to acknowledge the support of Sunchon National University, South Korea, through the BK21 + programme.

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Authors and Affiliations

  1. School of Engineering and Material Science, Queen Mary University of London, London, E1 4NS, UK

    Harshit Porwal, Salvatore Grasso & Mike J. Reece

  2. Nanoforce Technology Limited, London, E1 4NS, UK

    Harshit Porwal, Salvatore Grasso & Mike J. Reece

  3. International Center for Young Scientists (ICYS), National Institute for Materials Science (NIMS), Tsukuba, 305-0047, Japan

    Mehdi Estili

  4. Department of Materials Science and Engineering, Institute of Biomaterials, University of Erlangen-Nuremberg, Cauerstr. 6, 91058, Erlangen, Germany

    Alina Grünewald, Rainer Detsch & Aldo R. Boccaccini

  5. Materials Processing Unit, National Institute for Materials Science (NIMS), Tsukuba, 305-0047, Japan

    Chunfeng Hu & Yoshio Sakka

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  1. Harshit Porwal
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  2. Mehdi Estili
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Correspondence to Mehdi Estili, Aldo R. Boccaccini or Mike J. Reece.

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Porwal, H., Estili, M., Grünewald, A. et al. 45S5 Bioglass®–MWCNT composite: processing and bioactivity. J Mater Sci: Mater Med 26, 199 (2015). https://doi.org/10.1007/s10856-015-5529-9

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