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Enhanced antibacterial effect of silver nanoparticles obtained by electrochemical synthesis in poly(amide-hydroxyurethane) media

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An Erratum to this article was published on 14 June 2011

Abstract

In the present study, we report enhanced antimicrobial properties of 29 and 23 nm silver nanoparticles (Ag NPs) obtained by electrochemical synthesis in poly(amide-hydroxyurethane) media. Antibacterial activity assessed by disk diffusion method indicates that silver nanoparticles produced inhibition zones for both Escherichia coli and Staphylococcus aureus depending on silver concentration. The bacterial growth curve performed in the presence of silver nanoparticles showed a stronger antibacterial effect at lower concentrations than those described in the earlier reports. The effect was both dose and size dependent and was more pronounced against Gram negative bacteria than Gram positive one. The smallest Ag NPs used had a bactericidal effect resulting in killing E. coli cells. Scanning electron microscopy analysis indicated major damage and morphology changes of the silver nanoparticles treated bacterial cells. The major mechanism responsible for the antibacterial effect probably consists in clusters formation and nanoparticles anchorage to the bacterial cell surface.

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Acknowledgments

This study was supported by CNCSIS–UEFISCSU, 509 PNII–IDEI 1996/2008 research grant.

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Authors and Affiliations

  1. Faculty of Biology, “Alexandru Ioan Cuza” University, Iasi, Romania

    Stefan Marius, Hritcu Lucian, Mihasan Marius, Gostin Irina & Dunca Simona

  2. Faculty of Physics, COMB Laboratory, “Alexandru Ioan Cuza” University, Iasi, Romania

    Pricop Daniela & Melnig Viorel

  3. Faculty of Chemistry, “Alexandru Ioan Cuza” University, Iasi, Romania

    Olariu Romeo-Iulian

Authors
  1. Stefan Marius
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  2. Hritcu Lucian
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  3. Mihasan Marius
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Correspondence to Stefan Marius.

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An erratum to this article can be found at http://dx.doi.org/10.1007/s10856-011-4360-1

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Marius, S., Lucian, H., Marius, M. et al. Enhanced antibacterial effect of silver nanoparticles obtained by electrochemical synthesis in poly(amide-hydroxyurethane) media. J Mater Sci: Mater Med 22, 789–796 (2011). https://doi.org/10.1007/s10856-011-4281-z

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  • DOI: https://doi.org/10.1007/s10856-011-4281-z

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