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Macrocycles embedding phenothiazine or similar nitrogen and/or sulphur containing heterocycles

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Abstract

Macrocycles emerged as an important class of useful compounds with multiple applications ranging from selective complexation of different anions, cations or neutral molecules to the development of new sensors, materials with improved properties and biologically active compounds. In this review we focus our discussion on the synthesis and structural analysis of macrocycles containing dibenzoheterocycles with sulphur and/or nitrogen atoms in the central six-membered ring (i.e. 10H-phenothiazine, 9,10-dihydroacridine or acridane, acridone, thianthrene, phenoxathiine, acridine, phenazine). We further highlight selected application of these compounds as host molecules, DNA intercalating agents or enzyme inhibitors.

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Acknowledgments

We are grateful for the financial support of this work by CNCS-UEFISCDI (Project PN-II-ID-JRP-RO-FR-2012-0088).

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Authors and Affiliations

  1. Supramolecular Organic and Organometallic Chemistry Center (SOOMCC), Babeş-Bolyai University, 11 Arany Janos Street, 400028, Cluj-Napoca, Romania

    Monica Irina Rednic, Niculina D. Hădade, Elena Bogdan & Ion Grosu

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  1. Monica Irina Rednic
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  2. Niculina D. Hădade
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  3. Elena Bogdan
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  4. Ion Grosu
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Correspondence to Elena Bogdan or Ion Grosu.

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Rednic, M.I., Hădade, N.D., Bogdan, E. et al. Macrocycles embedding phenothiazine or similar nitrogen and/or sulphur containing heterocycles. J Incl Phenom Macrocycl Chem 81, 263–293 (2015). https://doi.org/10.1007/s10847-014-0455-x

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  • DOI: https://doi.org/10.1007/s10847-014-0455-x

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