Skip to main content
Log in

Atrioventricular Nodal Reentrant Tachycardia with Paroxysmal Atrial Fibrillation: Clinical and Electrophysiological Features and Predictors of Atrial Fibrillation Recurrence Following Elimination of Atrioventricular Nodal Reentrant Tachycardia

  • Published:
Journal of Interventional Cardiac Electrophysiology Aims and scope Submit manuscript

Abstract

Introduction: Clinical and electrophysiological characteristics of patients with atrioventricular nodal reentrant tachycardia (AVNRT) and paroxysmal atrial fibrillation (AF) have not been studied in a large patient cohort. We aimed to define the clinical features and cardiac electrophysiological characteristics of these patients, and to examine the incidence and identify predictors of AF recurrences after elimination of AVNRT.

Methods and Results: Thirty-six patients with AVNRT and documented paroxysmal AF (Group 1) and 497 patients with AVNRT alone undergoing ablation in the same period (Group 2) were studied. There were no significant differences between groups regarding clinical features, except age, which was higher in Group 1 (p < 0.001). Presence of atrial vulnerability (induction of AF lasting > 30 seconds) and multiple AH jumps (≥50 ms) before ablation were significantly more prevalent in Group 1 (p < 0.001, p = 0.010 respectively). During follow-up of 34 ± 11 months, AF recurred in 10 patients (28%) in Group 1, while 2 patients in Group 2 (0.4%) developed paroxysmal AF (p < 0.001). Univariate predictors of AF were: left atrial diameter > 40 mm (p = 0.001), presence of mitral or aortic calcification (p = 0.003), atrial vulnerability after ablation (p = 0.015) and valvular disease (p = 0.042). However, independent predictors of AF recurrences were left atrial diameter > 40 mm (p = 0.002) and the presence of atrial vulnerability after ablation (p = 0.034).

Conclusion: In patients with both AVNRT and paroxysmal AF, the recurrence rate of AF after elimination of AVNRT is 28%. Left atrial diameter greater than 40 mm and atrial vulnerability after elimination of AVNRT are independent predictors of AF recurrences in the long term.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Elvas L, Gursoy S, Brugada J, Andries E, Brugada P. Atrioventricular nodal reentrant tachycardia:A review. Can J Cardiol 1994;10:342–348.

    PubMed  Google Scholar 

  2. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke:The Framingham Study. Stroke 1991;22:983–988.

    PubMed  Google Scholar 

  3. Hurwitz JL, German LD, Packer DL, Wharton JM, McCarthy EA, Wilkinson WE, Prystowsky EN, Pritchett EL. Occurrence of atrial fibrillation in patients with paroxysmal supraventricular tachycardia due to atrioventricular nodal reentry. Pacing Clin Electrophysiol 1990;13:705–710.

    PubMed  Google Scholar 

  4. Hamer ME, Wilkinson WE, Clair WK, Page RL, McCarthy EA, Pritchett EL. Incidence of symptomatic atrial fibrillation in patients with paroxysmal supraventricular tachycardia. J Amer Coll Cardiol 1995;25:984–988.

    Article  Google Scholar 

  5. Haissaguerre M, Gaita F, Fischer B, Commenges D, Montserrat P, d'Ivernois C, Lemetayer P, Warin JF. Elimination of atrioventricular nodal reentrant tachycardia using discrete slow potentials to guide application of radiofrequency energy. Circulatio 1992;85:2162–2175.

    PubMed  Google Scholar 

  6. Leitch J, Klein GJ, Yee R, Murdock C. Invasive electrophysiologic evaluation of patients with supraventricular tachycardia. Cardiol Clin 1990;8:465–477.

    PubMed  Google Scholar 

  7. Kose S, Amasyali B, Aytemir K, Kilic A, Can I, Kursaklioglu H, Celik T, Isik E. Atrioventricular nodal reentrant tachycardia with multiple discontinuities in the atrioventricular node conduction curve:Immediate success rates of radiofrequency ablation and long-term clinical follow-up results as compared to patients with single or no AH-jumps. J Interv Card Electrophysiol 2004;10:249–254.

    Article  PubMed  Google Scholar 

  8. D'Este D, Pasqual A, Bertaglia M, Meneghello MP, Zanocco A, Delise P, D'Este F, Pascotto P. Evaluation of atrial vulnerability with transesophageal stimulation in patients with atrioventricular junctional reentrant tachycardia. Comparison with patients with ventricular pre-excitation and with normal subjects. Eur Heart J 1995;16:1632–1636.

    PubMed  Google Scholar 

  9. Calkins H, el-Atassi R, Kalbfleisch S, Langberg J, Morady F. Effects of an acute increase in atrial pressure on atrial refractoriness in humans. Pacing Clin Electrophysiol 1992;15:1674–1680.

    PubMed  Google Scholar 

  10. Calkins H, Maughan WL, Kass DA, Sagawa K, Levine JH. Electrophysiological effect of volume load in isolated canine hearts. Amer J Physiol 1989;256:H1697–H1706.

    PubMed  Google Scholar 

  11. Zipes DP, Mihalick MJ, Robbins GT. Effects of selective vagal and stellate ganglion stimulation of atrial refractoriness. Cardiovasc Res 1974;8:647–655.

    PubMed  Google Scholar 

  12. Buxton AE, Waxman HL, Marchlinski FE, Josephson ME. Atrial conduction:Effects of extrastimuli with and without atrial dysrhythmias. Amer J Cardiol 1984;54:755–761.

    PubMed  Google Scholar 

  13. Cosio FG, Palacios J, Vidal JM, Cocina EG, Gomez-Sanchez MA, Tanargo L. Electrophysiologic studies in atrial fibrillation:Slow conduction of premature impulses:A possible manifestation of the background for reentry. Amer J Cardiol 1983;51:122–130.

    PubMed  Google Scholar 

  14. Papageorgiou P, Monahan K, Boyle NG, Seifert MJ, Beswick P, Zebede J, Epstein LM, Josephson ME. Site-dependent intra-atrial conduction delay. Relationship to initiation of atrial fibrillation. Circulation 1996;94:384–389.

    PubMed  Google Scholar 

  15. Chen YJ, Tai CT, Hsieh MH, Tsai CF, Lin WS, Chen SA. Dependence of electrogram duration in right posteroseptal atrium and atrium-pulmonary vein junction on pacing site:Mechanism and implications regarding atrioventricular nodal reentrant tachycardia and paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol 2000;11:506–515.

    PubMed  Google Scholar 

  16. Delise P, Gianfranchi L, Paparella N, Brignole M, Menozzi C, Themistoclakis S, Mantovan R, Bonso A, Coro L, Vaglio A, Ragazzo M, Alboni P, Raviele A. Clinical usefulness of slow pathway ablation in patients with both paroxysmal atrioventricular nodal reentrant tachycardia and atrial fibrillation. Amer J Cardiol 1997;79:1421–1423.

    Article  PubMed  Google Scholar 

  17. Brugada J, Mont L, Matas M, Navarro-Lopez F. Atrial fibrillation induced by atrioventricular nodal reentrant tachycardia. Amer J Cardiol 1997;79:681–682.

    Article  PubMed  Google Scholar 

  18. Weiss R, Knight BP, Bahu M, Zivin A, Souza J, Goyal R, Daoud E, Man KC, Strickberger SA, Morady F. Long-term follow-up after radiofrequency ablation of paroxysmal supraventricular tachycardia in patients with tachycardia-induced atrial fibrillation. Amer J Cardiol 1997;80:1609–1610.

    Article  PubMed  Google Scholar 

  19. Anselme F, Frederiks J, Papageorgiou P, Monahan KM, Epstein LM, Spach MS, Josephson ME. Nonuniform anisotropy is responsible for age-related slowing of atrioventricular nodal reentrant tachycardia. J Cardiovasc Electrophysio 1996;7:1145–1153.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Basri Amasyali MD.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Amasyali, B., Kose, S., Aytemir, K. et al. Atrioventricular Nodal Reentrant Tachycardia with Paroxysmal Atrial Fibrillation: Clinical and Electrophysiological Features and Predictors of Atrial Fibrillation Recurrence Following Elimination of Atrioventricular Nodal Reentrant Tachycardia. J Interv Card Electrophysiol 13, 195–201 (2005). https://doi.org/10.1007/s10840-005-2225-6

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10840-005-2225-6

Keywords

Navigation